Risk assessment is the cornerstone of working safely with biological agents. The World Health Organization (WHO) Laboratory Biosafety Manual Fourth Edition Monograph on Risk Assessment provides stepwise guidance for carrying out a risk assessment, from gathering information and identifying hazards to evaluating the risks and developing and implementing controls and review.To support the development of a mature safety culture within laboratories, it is important that all staff who handle biological agents understand the process of risk assessment and receive training in identifying hazards and mitigating risk. All personnel can partake in risk assessments, and the guidance is written in such a way that it is applicable to all-not just to biosafety professionals, laboratory scientists, or facility managers.Here we take the guidance from WHO and apply the principles of risk assessment to working with ASFV, illustrating the process using an example activity-the passage of low titer ASFV in cell culture. We discuss other techniques and protocols that you may need to consider when working with ASFV.
Background: Delirium is common in hospitalized patients and correlated with increased morbidity and mortality. Despite this, delirium is underdiagnosed, and many institutions do not have sufficient resources to consistently apply effective screening and prevention.
Objective: To develop a machine learning algorithm to identify patients at highest risk of delirium in the hospital each day in an automated fashion based on data available in the electronic medical record, reducing the barrier to large-scale delirium screening.
The increasing occurrence of infections caused by multidrug-resistant (MDR) bacteria drives the need for new antibacterial drugs. Due to the current lack of antibiotic discovery and development, new strategies to fight MDR bacteria are urgently needed. Efforts to develop new antibiotic adjuvants to increase the effectiveness of existing antibiotics and design delivery systems are essential to address this issue.
Introduction: Retinol has a long history of treating skin conditions, including photoaging. However, skin irritation with repeated use of retinol is well documented. The present study assessed the effectiveness of a novel topical formulation, referred to as retinol topical formulation (RTF), to improve the quality of skin health.
One Health approaches emphasize intersections between animal health, environmental well-being and human health. Unfortunately, one health approaches rarely explicitly encompass occupational health and safety. This short report provides a concise introduction to the One Health principle, highlighting its potential relevance to improving occupational health and safety in aquaculture.
Objectives: The aim of this study was to describe the safety and effectiveness of thoracic or lumbar partial lateral corpectomy (PLC) in cats with spinal cord compression due to intervertebral disc herniation (IVH).
Methods: A retrospective study was conducted of 12 client-owned cats from two academic and one private referral veterinary centres. Cross-sectional imaging was available in 12 cats for evaluation of disc herniation.
