Intestinal Perforation as a Paradoxical Reaction to Tuberculosis.

Cureus

Family Medicine, Ambulatory Health Services, Al Ain, ARE.

Published: April 2022

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Article Abstract

Paradoxical reactions (PR) to tuberculosis (TB) treatments are characterized by an initial improvement of the clinical symptoms followed by a clinical or radiological deterioration of existing TB lesions or by the development of new lesions. PR in the gastrointestinal system is a rare phenomenon. Moreover, intestinal perforation is an uncommon but potentially fatal complication of intestinal TB. We report the case of a 29-year-old female who presented with fever and abdominal pain that was associated with watery diarrhea. She was diagnosed as a case of intestinal TB. During her stay, she developed intestinal perforation following the initiation of anti-TB treatment. She was eventually managed as a case of intestinal perforation as a PR to TB.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098107PMC
http://dx.doi.org/10.7759/cureus.24077DOI Listing

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