Case Summary: A 7-month-old female neutered Bengal cat was referred to the Queen Mother Hospital for Animals following unknown trauma. Clinical and radiographic examination revealed a grade IIIB open, comminuted, mid-diaphyseal fracture of the left tibia and fibula, and grade IIIB open mid-diaphyseal fractures of the left metatarsals II-V. The fractures were stabilised with tibial and metatarsal external skeletal fixators. The open wounds were initially debrided surgically using conventional dressings, resulting in a small amount of circumferential granulation tissue formation by 10 days postoperatively. Following this 10-day period of conventional wound management, negative pressure wound therapy (NPWT) was applied over the external skeletal fixators and wounds. After 8 days of NPWT complete granulation tissue coverage was achieved in the tibial wound, and only small areas of two metatarsals remained exposed. The tibial wound was left to heal by second intention; a free meshed skin graft was applied to the pedal wound. Twenty weeks postoperatively, all wounds had completely healed and revision surgery with internal fixation was performed to treat a non-union of the tibia. Thirty weeks after the initial surgery, radiographic union of the tibia and metatarsals II-IV was confirmed.
Relevance And Novel Information: This is the first report of NPWT application over external fixation for the management of wounds associated with open fractures in veterinary medicine. This case was presented to introduce a novel, well-tolerated and simple technique for the management of tissue loss over an open fracture immobilised with external fixation.
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http://dx.doi.org/10.1177/20551169221092654 | DOI Listing |
Org Lett
January 2025
Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741246, India.
An electrochemical strategy for the regioselective construction of seleno-benzothiophenes/furans is reported through electrochemical selenocyclization, followed by Wagner-Meerwein rearrangement. This electro-oxidative tandem process operates under metal-free and external chemical oxidant-free conditions. Advantageously, unprotected homopropargyl alcohols were found to be compatible under the reaction conditions, releasing water and dihydrogen as the biproduct.
View Article and Find Full Text PDFVet Surg
January 2025
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Objective: To report clinical outcomes of skeletally immature dogs with antebrachial deformities secondary to premature closure of the distal radial physis (PCDRP) treated with angular corrections and distraction osteogenesis using circular external skeletal fixation (CESF).
Study Design: Retrospective multi-institutional case series.
Animals: A total of 12 client-owned dogs with premature distal radial physeal closure.
Int Urogynecol J
January 2025
Department of Clinical Anatomy, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8510, Japan.
Introduction And Hypothesis: The urethra is surrounded by layers of smooth muscle, including inner longitudinal and outer circler muscles, as well as the skeletal muscle of the external urethral sphincter. However, the extent of these muscles and their relationship with the levator ani (LA) remain unclear. This study aimed to clarify the composition of muscle layers around the female urethra and their three-dimensional arrangements.
View Article and Find Full Text PDFNeuropathol Appl Neurobiol
February 2025
Department of Neurology, Shandong Key Laboratory of Mitochondrial Medicine and Rare Diseases, Research Institute of Neuromuscular and Neurodegenerative Diseases, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Background: Progressive external ophthalmoplegia (PEO) is a classic manifestation of mitochondrial disease. However, the link between its genetic characteristics and clinical presentations remains poorly investigated.
Methods: We analysed the clinical, pathological and genetic characteristics of a large cohort of patients with PEO, based on the type of their mtDNA variations.
J Relig Health
January 2025
Ecole Biblique et Archéologique Française, Couvent Saint-Etienne, 83-85 Nablus Road/Derekh Shekhem, P.O.B. 19053, Jerusalem, Israel.
Anthropological and palaeopathological examination of four male skeletons from Qumran (Near-East) revealed skeletal lesions that may be linked to an intense practice of traditional Jewish rituals within this hyper-religious community of the first-century CE: chronic inflammation of the external auditory canals linked to frequent immersion in sacred baths (mikvah), and osteo-articular lesions following intense and repeated genuflection and anteflexion of the trunk.
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