Synthesis and Characterization of Alkyne-Functionalized Photo-Cross-Linkable Polyesters.

ACS Omega

Meinig School of Biomedical Engineering, College of Engineering, Cornell University, Ithaca, New York 14853, United States.

Published: May 2022

AI Article Synopsis

  • An alkyne-functionalized elastomer is created using sebacic acid, 1,3-propanediol, and alkyne-functionalized serinol through a melt condensation process.
  • A low-power UV lamp initiates quick cross-linking via thiol-yne click chemistry, which is analyzed using photorheology and NMR spectroscopy.
  • The final elastomer shows mechanical properties comparable to human soft tissues and demonstrates degradability along with good cytocompatibility.

Article Abstract

An alkyne-functionalized elastomer derived from sebacic acid, 1,3-propanediol, and alkyne-functionalized serinol is synthesized via melt condensation. A low-power UV lamp triggers the cross-linking rapidly via thiol-yne click chemistry. The cross-linking behavior is studied by photorheology and NMR spectroscopy. The resultant elastomer possesses mechanical properties similar to those of human soft tissues and exhibits degradability and good cytocompatibility.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096926PMC
http://dx.doi.org/10.1021/acsomega.2c00272DOI Listing

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