Purpose: In radiotherapy, deformable image registration (DIR) has been frequently used in different imaging examinations in recent years. However, no phantom has been established for quality assurance for DIR. In order to develop a non-rigid phantom for accuracy control between CT and MRI images, we investigated the suitability of 3D printing materials and gel materials in this study.
Methods: We measured CT values, T values, T values, and the proton densities of 31 3D printer materials-purchased from three manufacturers-and one gel material. The dice coefficient after DIR was calculated for the CT-MRI images using a prototype phantom made of a gel material compatible with CT-MRI.
Results: The CT number of the 3D printing materials ranged from -6.8 to 146.4 HU. On MRI, T values were not measurable in most cases, whereas T values were not measurable in all cases; proton density (PD) ranged from 2.51% to 4.9%. The gel material had a CT number of 111.16 HU, T value of 813.65 ms, and T value of 27.19 ms. The prototype phantom was flexible, and the usefulness of DIR with CT and MRI images was demonstrated using this phantom.
Conclusion: The CT number and T and T values of the gel material are close to those of the human body and may therefore be developed as a DIR verification phantom between CT and MRI. These findings may contribute to the development of non-rigid phantoms for DIR in the future.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.6009/jjrt.2022-1241 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Emerging of Ultrafine Membraneless Organelles as the Missing Piece of Nanostress: Mechanism of Biogenesis and Implications at Multilevels.
ACS Nano
January 2025
Department of Pharmaceutics, and Nanjing Medical University, Nanjing 211166, P. R. China.
Understanding the interaction between nanomaterials and cellular structures is crucial for nanoparticle applications in biomedicine. We have identified a subtype of stress granules, called nanomaterial-provoked stress granules (NSGs), induced by gold nanorods (AuNRs). These NSGs differ from traditional SGs in their physical properties and biological functions.
View Article and Find Full Text PDFTwo-wavelength-selective Soft Actuators Comprising Thermosensitive and Lanthanoid-ion-coordinated Interpenetrating Polymer Network Gels.
J Oleo Sci
January 2025
Graduate School of Science and Technology, Kumamoto University.
Near-infrared wavelength-selective soft actuators have attracted much attention for applications in microsystems in bioliving. It is desirable for the photothermal conversion materials in the actuators to be downsized to the molecular scale. However, in conventional actuator materials using copolymer gels composed of thermosensitive and photothermal conversion molecule-coordinated monomers, the strong cross-linking of molecules in the networks impairs the actuator deformation.
View Article and Find Full Text PDFStabilised hyaluronic acid gel marker versus surgical clips for tumour bed delineation in breast cancer radiotherapy using MRI-simulation.
Radiother Oncol
January 2025
Department of Radiation Oncology Olivia Newton-John Cancer Wellness & Research Centre Austin Health Victoria Australia; Department of Medical Imaging and Radiation Sciences, Monash University Clayton Victoria Australia; Genesis Care, Ringwood Private Hospital Victoria Australia.
Background And Purpose: Compare breast cancer tumour bed (TB) delineation using stabilised hyaluronic acid (sHA) gel and MRI-simulation versus surgical clips and CT-simulation within same patient cohort.
Materials And Methods: Prospective single arm study of patients undergoing breast conserving surgery. Patients had both clips (≥5) and sHA gel markers inserted to define the TB and underwent MRI and CT simulation scans.
Development of high-strength, 3D-printable, and biocompatible gelatin/κ-carrageenan dual-network hydrogels for wound healing.
Int J Biol Macromol
January 2025
The Affiliated Qingyuan Hospital (Qingyuan People's Hospital), Guangzhou Medical University, Qingyuan, Guangdong Province 511518, China. Electronic address:
Gelatin/κ-carrageenan (Gel/KC) hydrogel has exhibited a significant potential in tissue engineering, however, there is still a need to further enhance its structural properties. This study developed a Gel/KC dual-network hydrogel with superior mechanical properties and structural stability, which was integrated with 3D printing to evaluate its ability to promote wound healing. The hydrogels with seven different Gel and KC ratios were prepared and characterized using rheological testing, thermal analysis, spectral analysis, micromorphology observation, and X-ray diffraction.
View Article and Find Full Text PDFPhase-separated condensates in autophagosome formation and autophagy regulation.
J Mol Biol
January 2025
National Laboratory of Biomacromolecules, New Cornerstone Science Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Biomacromolecules partition into numerous types of biological condensates or membrane-less organelles via liquid-liquid phase separation (LLPS). Newly formed liquid-like condensates may further undergo phase transition to convert into other material states, such as gel or solid states. Different biological condensates possess distinct material properties to fulfil their physiological functions in diverse cellular pathways and processes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!