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Effect of COVID-19 with or without acute kidney injury on inpatient mortality in England: a national observational study using administrative data.
BMJ Open
March 2025
Department of Renal Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.
Objectives: To evaluate hospital outcomes and their predictors during the pandemic for patients with and without COVID-19, stratified by the presence of acute kidney injury (AKI).
Design: Retrospective observation study using the Hospital Episodes Statistics database for England.
Participants: 2 385 337 unique hospital admissions of adult patients from March 2020 to March 2021 in England.
Objective: To examine the accuracy of the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA), the population-based clinical quality registry for people with kidney failure, in identifying Aboriginal and/or Torres Strait Islander people.
Design: Population-based cohort study of reporting accuracy.
Setting: New South Wales, 2006-2020.
Vonoprazan in Management of Refractory Gastroesophageal Reflux Disease: An Indian Expert Group Consensus Statements.
J Assoc Physicians India
March 2025
Assistant Professor, Department of Gastroenterology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Background: Approximately, 40% of gastroesophageal reflux disease (GERD) patients experience insufficient symptom relief from proton-pump inhibitors (PPI), resulting in PPI-refractory GERD (rGERD).
Objective: To review the existing literature and develop an Indian expert group consensus statement on the place of vonoprazan in the management of rGERD.
Materials And Methods: A panel of 35 leading Indian gastroenterologists extensively reviewed the literature to develop consensus statements for the management of rGERD in Indian patients, with a focus on the newly available potassium-competitive acid blocker (P-CAB), vonoprazan.
Transfusion of modified whole blood versus blood components therapy in patients with severe trauma: Randomized controlled trial protocol (WEBSTER trial).
Injury
January 2025
División de Cirugía de Trauma y Emergencias, Departamento de Cirugía, Fundación Valle del Lili, Cali, Colombia; Departamento de Cuidado Intensivo, Fundación Valle del Lili, Cali, Colombia; Departamento de Cirugía, Universidad del Valle, Cali, Colombia.
Hemostatic resuscitation is a mainstay in the management of trauma patients. Factors such as blood loss and tissue injury contribute to coagulation and hemodynamic status imbalances. Hemorrhage remains a leading cause of death in trauma patients, despite advances in strategies such as damage control surgery, massive transfusion protocol, and intensive care.
View Article and Find Full Text PDFReducing time for vascular access salvage: initial results from a single institution's clinical practice improvement programme.
BMJ Open Qual
March 2025
Department of General Surgery, Tan Tock Seng Hospital, Singapore.
Background: One of the most common causes of arteriovenous fistula (AVF) and/or arteriovenous graft (AVG) failure is thrombosis. Guidelines recommend early AVF salvage within 24-48 hours. Our institution reported poor compliance with these recommendations, with a median of 3 days prior to vascular access (VA) salvage.
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