Both humoral and cellular anamnestic responses are significant for protective immunity against SARS-CoV-2. In the current study, the responses in elderly people before and after a fourth vaccine dose of BNT162b2 were compared to those of individuals immunized with three vaccine doses. Although a boost effect was observed, the high response following the third administration questions the necessity of an early fourth boost.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101339PMC
http://dx.doi.org/10.3390/jcm11092649DOI Listing

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