Multifunctional nanocomposites that combine both magnetic and photoluminescent (PL) properties provide significant advantages for nanomedical applications. In this work, a one-stage synthesis of magneto-luminescent nanocomposites (MLNC) with subsequent stabilization is proposed. Microwave synthesis of magnetic carbon dots (M-CDs) was carried out using precursors of carbon dots and magnetic nanoparticles. The effect of stabilization on the morphological and optical properties of nanocomposites has been evaluated. Both types of nanocomposites demonstrate magnetic and PL properties simultaneously. The resulting MLNCs demonstrated excellent solubility in water, tunable PL with a quantum yield of up to 28%, high photostability, and good cytocompatibility. Meanwhile, confocal fluorescence imaging showed that M-CDs were localized in the cell nuclei. Consequently, the multifunctional nanocomposites M-CDs are promising candidates for bioimaging and therapy.
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http://dx.doi.org/10.3390/nano12091396 | DOI Listing |
Environ Sci Pollut Res Int
January 2025
Biofuel Laboratory, Department of Energy, Tezpur University, Assam, 784028, India.
Agro-processing industries generate a substantial quantity of biomass wastes. Conversion of these wastes into valuable material could be profitable considering both environmental and economic aspects. Among various biomass conversion methods, hydrothermal conversion can be used for co-production of biofuel and other valuable materials like carbon quantum dots (CQDs) and activated carbons.
View Article and Find Full Text PDFAnal Methods
January 2025
School of Public Health, Hebei Medical University, Shijiazhuang, 050017, P.R. China.
In this study, a molecularly imprinted electrochemical sensor (MIECS) was constructed based on the combination of graphene quantum dots-gold nanoparticles (GQDs-AuNPs), molecular imprinting polymer (MIP), and electrochemical technology for the ultra-sensitive detection of 17β-estradiol (E). GQDs-AuNPs were synthesized and modified on the surface of glassy carbon electrodes (GCE). Safranine T was used as the functional monomer and E was the template molecule for self-assembly and electropolymerization, thus generating an MIP film on the electrode surface.
View Article and Find Full Text PDFLuminescence
January 2025
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University, Cairo, Egypt.
Affordable and eco-friendly green spectrofluorometric (FL) methods can enhance the safety and cost-effectiveness of quality assurance and control in ascorbic acid (ASA) formulations. However, most current techniques for ASA analysis have faced challenges like complexity, delayed response times, low throughput, time-consuming procedures, and requirements for expensive equipment and hazardous chemicals for analyte modification. The study is aimed at producing natural carbon quantum dots (NACQDs) from pumpkin seed peels (PSPs), a natural waste material, using a rapid microwave-assisted method.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Basic Medical Sciences, Shanxi Medical University, Taiyuan 030001, P. R. China.
Colon cancer is one kind of malignant digestive tract tumor with high morbidity and mortality worldwide, treatments for which still face great challenges. Recently emerged intervention strategies such as phototherapy and gas therapy have displayed promising effects in the treatment of colon cancer, but their application are still hindered due to insufficient tumor targeting and deeper tissue penetrating capacity. Herein, in the present study, we developed one theranostic nanoplatform Cet-CDs-SNO (CCS) to realize multimodal imaging-guided synergistic colon cancer therapy.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Horticultural Science, Faculty of Agriculture, University of Maragheh, Maragheh, 55181-83111, Iran.
Salinity is one of the predominant abiotic stressors that reduce plant growth, yield, and productivity. Ameliorating salt tolerance through nanotechnology is an efficient and reliable methodology for enhancing agricultural crops yield and quality. Nanoparticles enhance plant tolerance to salinity stress by facilitating reactive oxygen species detoxification and by reducing the ionic and osmotic stress effects on plants.
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