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http://dx.doi.org/10.1016/S2214-109X(22)00207-8 | DOI Listing |
Front Med (Lausanne)
February 2025
Department of Traditional Chinese Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Chemoresistance is a critical factor compromising the survival of patients with colorectal cancer (CRC). The "Zhi-Zhen" formula (ZZF), a traditional prescription developed by Chinese national medicine masters, has been extensively used in clinical practice to treat gastrointestinal cancer. Notably, ZZF has the potential to enhance tumor sensitivity to chemotherapy.
View Article and Find Full Text PDFJ Epidemiol Glob Health
March 2025
Precision Medicine Research Center, Sichuan Provincial Key Laboratory of Precision Medicine and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
Background: Older outpatients face a heightened risk of potentially inappropriate prescribing (PIP). However, there is a paucity of evidence evaluating PIP in older outpatients attending surgical outpatient departments in China using Chinese-specific criteria. This study aimed to assess the prevalence of PIP and identify associated factors within this population.
View Article and Find Full Text PDFImportance: Exercise intervention studies have shown benefits for patients with lung cancer undergoing surgery, yet most interventions to date have been resource intensive and have followed a one-size-fits-all approach.
Objective: To determine whether a personalized, clinic-aligned perioperative exercise program with remote monitoring and instructions can improve physical function and fatigue among patients undergoing surgery for lung cancer.
Design, Setting, And Participants: The Precision-Exercise-Prescription (PEP) randomized clinical trial is a single-center phase 3 trial.
Aging Dis
February 2025
International Center for Neuroscience Research, Institute for Intelligent Research, Tbilisi, Georgia.
This paper provides a thorough examination of aging-related diseases, exploring into the intricate molecular mechanisms that underline their development and progression. It explores cutting-edge therapeutic interventions aimed at addressing these conditions, with a particular focus on non-pharmacological approaches such as personalized lifestyle modifications, cognitive enhancement strategies, and robust social engagement initiatives. Additionally, it highlights emerging modalities including gene therapy and precision medicine as promising avenues for mitigating the challenges associated with age-related ailments.
View Article and Find Full Text PDFJ Pharm Biomed Anal
March 2025
Wroclaw University of Science and Technology, Faculty of Medicine, Department of Social Sciences and Infectious Diseases, 27 Wybrzeże Wyspiańskiego, Wrocław 50370, Poland.
The global opioid crisis is a public health emergency characterized by the widespread misuse of opioid drugs, leading to high rates of addiction, overdose, and death. Initially driven by the over-prescription of opioid painkillers, it has evolved into a worldwide epidemic exacerbated by the rise of potent synthetic opioids. Benzimidazole opioids ('nitazenes') are one group within this class of compounds that have garnered increasing attention in recent years due to their addictive potential and growing presence in illicit drug markets.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!