Super-resolution microscopy for the study of store-operated calcium entry.

Cell Calcium

Departamento de Biología Celular y del Desarrollo, Universidad Nacional Autónoma de México, CDMX 04510, Mexico. Electronic address:

Published: June 2022

The use of a variety of techniques based on super-resolution (SR) microscopy unveiled a close and complex relationship between cytoskeleton reorganization and SOCE. By using SR microscopy many new proteins involved in SOCE regulation have been identified over the last few years. Many enigmas remain unsolved in this highly dynamic field, however, recent developments in SR microscopy promise new answers soon. In the present review, we describe the most relevant findings in SOCE components and SOCE modulation using different methods derived from SR microscopy.

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http://dx.doi.org/10.1016/j.ceca.2022.102595DOI Listing

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