Traditional sequential pattern mining methods were designed for symbolic sequence. As a collection of measurements in chronological order, a time series needs to be discretized into symbolic sequences, and then users can apply sequential pattern mining methods to discover interesting patterns in time series. The discretization will not only cause the loss of some important information, which partially destroys the continuity of time series, but also ignore the order relations between time-series values. Inspired by order-preserving matching, this article explores a new method called order-preserving sequential pattern (OPP) mining, which does not need to discretize time series into symbolic sequences and represents patterns based on the order relations of time series. An inherent advantage of such representation is that the trend of a time series can be represented by the relative order of the values underneath time series. We propose an OPP-Miner algorithm to mine frequent patterns in time series with the same relative order. OPP-Miner employs the filtration and verification strategies to calculate the support and uses the pattern fusion strategy to generate candidate patterns. To compress the result set, we also study to find the maximal OPPs. Experimental results validate that OPP-Miner is not only efficient but can also discover similar subsequences in time series. In addition, case studies show that our algorithms have high utility in analyzing the COVID-19 epidemic by identifying critical trends and improve the clustering performance. The algorithms and data can be downloaded from https://github.com/wuc567/Pattern-Mining/tree/master/OPP-Miner.
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http://dx.doi.org/10.1109/TCYB.2022.3169327 | DOI Listing |
Theor Appl Genet
January 2025
Research Center for Life Sciences Computing, Zhejiang Lab, Hangzhou, 310012, China.
In the present study, we identified 22 significant SNPs, eight stable QTLs and 17 potential candidate genes associated with 100-seed weight in soybean. Soybean is an economically important crop that is rich in seed oil and protein. The 100-seed weight (HSW) is a crucial yield contributing trait.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
January 2025
Université Joseph KI-ZERBO, Laboratoire de Biologie Moléculaire et de Génétique (LABIOGENE), 03 BP 7021 Ouagadougou 03, Burkina Faso.
Hepatitis B virus (HBV) is a significant cause of liver disease and cancer worldwide. Understanding the genetic factors influencing HBV evolution is crucial for developing effective prevention and treatment strategies. Host genetic and environmental factors particularly influence the evolution of this infection.
View Article and Find Full Text PDFJ Periodontal Res
January 2025
Department of Surgery, Stanford University School of Medicine, Stanford, California, USA.
Aim: To investigate additional factors contributing to the pathophysiology of chemotherapy-induced oral mucositis and periodontitis beyond the systemic immune suppression caused by the chemotherapeutic agent 5-Fluorouracil (5-FU).
Methods: 5-Fluorouracil was topically delivered to the non-keratinized, rapidly proliferating junctional epithelium (JE) surrounding the dentition, and acts as an immunologic and functional barrier to bacterial ingression. Various techniques, including EdU incorporation, quantitative immunohistochemistry (qIHC), histology, enzymatic activity assays, and micro-computed tomographic (μCT) imaging, were employed to analyze the JE at multiple time points following topical 5-FU treatment.
Pak J Pharm Sci
January 2025
Jian'ou Municipal Hospital, Nanping, Fujian, China.
This article primarily discusses the efficacy and safety of atropine (ATR) plus omeprazole (OME) for the treatment of acute gastritis (AG). From May 2022 to May 2024, 95 AG patients were selected, including 50 cases treated with ATR+OME (observation group) and 45 cases with anisodamine (ADM) plus OME (control group). Comparative analyses of the following dimensions were then carried out: Clinical efficacy, safety (xerostomia, palpitations and headaches), symptom remission time (stomach pain, abdominal distension and nausea and vomiting), serum inflammatory factors (tumor necrosis factor [TNF]-α, interleukin [IL]-6 and interferon [IFN]-β) and plasma gastrointestinal hormones (epidermal growth factor [EGF], gastrin [GAS] and somatostatin [SS]).
View Article and Find Full Text PDFJ Public Health (Oxf)
January 2025
Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham NG5 1PB, UK.
Background: Alcohol misuse is linked to numerous health and socioeconomic harms. Edutainment and docutainment television programmes can act as health promotion tools, influencing health perceptions and behaviours. Inaccurate portrayals can engender misinformation.
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