Similar Publications

Deep eutectic solution elution assisted ligand affinity assay: A useful tool for the active coumarins screening from Fructus cnidii.

Anal Chim Acta

January 2025

Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, 300070, Tianjin, China. Electronic address:

Background: Many of the ligand affinity analyses are presented in water environment, and the hydrophilic solution such as methanol is used for dissociating the bound compounds. The obtained dissociation solution needs to be concentrated for improving the sensitivity of the assay. However, it is not good for the analysis of hydrophobic and volatile compounds such as coumarins.

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Background: Capillary electrophoresis (CE) is a highly versatile separation technique widely used in analytical chemistry. Traditionally, CE can be categorized as either aqueous or non-aqueous systems based on the buffer solvents employed. For decades, non-aqueous CE has been predominantly associated with the use of organic solvents, a perception deeply ingrained in the scientific community.

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Nano structural regulation of lignin and evaluation of its ultraviolet light absorption properties through quantum chemistry calculations.

Int J Biol Macromol

January 2025

Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Materials Science and Engineering, Nanjing Forestry University, Nanjing 210037, China.

Lignin, a biomass-derived material containing chromophores, possesses the potential to serve as a versatile organic ultraviolet (UV) light screening agent. By employing quantum chemical computation techniques, an amphoteric deep eutectic solvent (DES) based on sulfamic acid was purposefully designed and engineered to create a solvent system tailored for the nanoparticle formation and functionalization of lignin. As confirmed by experimental evidence, the size of the modified lignin nanoparticles (LNPs) varies from 168.

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This study aimed to enhance inulinase production from agricultural biomass pretreated with deep eutectic solvents (DES) using Aspergillus niger A42 (ATCC 204447). Barley husk (BH), wheat bran (WB), and oat husk (OH) were selected as substrates and were pretreated using different molar ratios of choline chloride: glycerol (ChCl: Gly) and choline chloride: acetic acid (ChCl: AA). DES pretreatment was followed by dilute sulfuric acid hydrolysis.

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Self-association of cyclodextrin inclusion complexes in a deep eutectic solvent enhances guest solubility.

Carbohydr Polym

March 2025

Institute of Chemistry, The Fritz Haber Research Center, and The Harvey M. Krueger Family Center for Nanoscience and Nanotechnology, Edmond J. Safra Campus, The Hebrew University, Jerusalem 9190401, Israel. Electronic address:

Cyclodextrins are widely used pharmaceutical excipients known to increase the solubility of drug compounds through formation of inclusion complexes. A prominent limitation of common cyclodextrins is their own scarce solubility in water, which renders them unsuitable for many drug formulations. Cyclodextrin solubility can be enhanced in appropriate media such as Deep Eutectic Solvents (DESs).

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