This paper describes the preparation and characterization of soy protein isolate (SPI)-collagen self-assembled nanomicelles. Novel SPI-collagen self-assembled nanomicelles hydrogen bonding and electrostatic interactions were developed. SPI-collagen soluble complexes were formed at pH 6.4, which was lower than the isoelectric point of collagen (pI = 7.8) and higher than that of SPI (pI = 4.5). This research mainly focuses on the intermolecular force between the SPI and collagen. The diameter distribution, critical association concentration, and stability of the SPI-collagen self-assembled nanomicelles were investigated in this research. It was found that the SPI and collagen had hydrogen bonding and electrostatic interactions, and then formed natural complex nanomicelles in a weakly acidic environment. The preparation of SPI-collagen self-assembled nanomicelles was performed in an aqueous environment without surfactants or toxic agents. As a fixing agent, transglutaminase (TGase) promoted the intra- and intermolecular cross-linking of the nanomicelles, which improved the stability of the self-assembled nanomicelles. The SPI-collagen nanomicelles had a good stability. This research may provide a reference for the utilization of SPI-collagen self-assembled nanomicelles.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089279 | PMC |
| http://dx.doi.org/10.1039/c8ra08030e | DOI Listing |
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