Humans and chimpanzees both exhibit a diverse set of tool use skills which suggests selection for tool manufacture and use occurred in the common ancestors of the two species. Our group has previously reported phenotypic and genetic associations between tool use skill and gray matter covariation, as quantified by source-based morphometry (SBM), in chimpanzees. As a follow up study, here we evaluated repeatability in heritability in SBM components and their phenotypic association with tool use skill in two genetically independent chimpanzee cohorts. Within the two independent cohorts of chimpanzees, we identified 8 and 16 SBM components, respectively. Significant heritability was evident for multiple SBM components within both cohorts. Further, phenotypic associations between tool use performance and the SBM components were largely consistent between the two cohorts; the most consistent finding being an association between tool use performance and an SBM component including the posterior superior temporal sulcus (STS) and superior temporal gyrus (STG), and the interior and superior parietal regions (p < 0.05). These findings indicate that the STS, STG, and parietal cortices are phenotypically and genetically implicated in chimpanzee tool use abilities.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351395 | PMC |
| http://dx.doi.org/10.1016/j.neuroimage.2022.119292 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
regionalpcs improve discovery of DNA methylation associations with complex traits.
Nat Commun
January 2025
Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
We have developed the regionalpcs method, an approach for summarizing gene-level methylation. regionalpcs addresses the challenge of deciphering complex epigenetic mechanisms in diseases like Alzheimer's disease. In contrast to averaging, regionalpcs uses principal components analysis to capture complex methylation patterns across gene regions.
View Article and Find Full Text PDFRadiation-induced aberrant structural covariance networks in patients with nasopharyngeal carcinoma: a source-based morphometry study.
Quant Imaging Med Surg
December 2024
Department of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Background: Radiation-induced brain injury (RBI) is a common complication in patients with nasopharyngeal carcinoma (NPC) who have undergone radiotherapy (RT), which is characterized by significant cognitive and psychological impairments. Although radiation-induced regional structural abnormalities have been well-reported, the effects of RT on the whole brain structural covariance networks are mostly unknown. Here, we performed a source-based morphometry (SBM) study to solve this issue.
View Article and Find Full Text PDFCell Type Differentiation Using Network Clustering Algorithms.
bioRxiv
December 2024
Observatory of Social Media, Luddy School of Informatics, Computing, and Engineering, Indiana University, Indiana, USA.
Single cell RNA-seq (scRNA-seq) technologies provide unprecedented resolution representing transcriptomics at the level of single cell. One of the biggest challenges in scRNA-seq data analysis is the cell type annotation, which is usually inferred by cell separation approaches. In-silico algorithms that accurately identify individual cell types in ongoing single-cell sequencing studies are crucial for unlocking cellular heterogeneity and understanding the biological basis of diseases.
View Article and Find Full Text PDFSwachh Bharat Mission Gramin: Uptake and challenges in rural Coimbatore.
J Family Med Prim Care
October 2024
Department of Community Medicine, KMCHIHSR, Tamil Nadu, India.
Introduction: Water, sanitation, and hygiene (WASH)-related infectious diseases contribute to approximately 5% of the global disease burden. Despite sanitation being a human right, 673 million people worldwide had limited access to toilets. To tackle the same, Swachh Bharat Mission-Gramin (SBM-G) was launched in 2014 to facilitate the construction of over 100 million individual household latrines (IHHLs) across India.
View Article and Find Full Text PDFComparative analysis of intestinal microbiota and its function on digestion and immunity of juvenile abalone Haliotis discus hannai fed two different sources of dietary soybean protein.
Fish Shellfish Immunol
November 2024
The Key Laboratory of Aquaculture Nutrition and Feeds (Ministry of Agriculture and Rural Affairs), The Key Laboratory of Mariculture (Ministry of Education), Fisheries College, Ocean University of China, Qingdao, 266003, China. Electronic address:
Article Synopsis
- - The study assessed how replacing fish meal with soybean protein sources (SPC and SBM) affects the intestinal microbiota of abalone (Haliotis discus hannai) and their health over a 110-day feeding period.
- - While overall diversity in microbiota (α-diversity) remained similar across groups, significant changes in specific gut bacteria were observed, with high numbers of unique bacterial types (OTUs) in the SBM50 group and lower in the control (FM).
- - Importantly, the SPC25 group showed reduced pathogenic bacteria, and specific diets influenced digestive and immune functions, indicating that feeding 50% SBM and 25% SPC promotes healthier intestinal microbiota in abalone.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!