Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and -methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9084380 | PMC |
| http://dx.doi.org/10.1039/c8ra05338c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The role of artificial intelligence in preoperative planning for Total Hip Arthroplasty: a systematic review.
Front Artif Intell
December 2024
Department of Orthopedic Hip and Knee Surgery, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Background: Total Hip Arthroplasty (THA) is a transformative surgical intervention for hip joint disorders, necessitating meticulous preoperative planning for optimal outcomes. With the emergence of Artificial Intelligence (AI), preoperative planning paradigms have evolved, leveraging AI algorithms for enhanced decision support and imaging analysis. This systematic review aims to comprehensively evaluate the role of AI in THA preoperative planning, synthesizing evidence from studies exploring various AI techniques and their applications.
View Article and Find Full Text PDFCAZymes ( C arbohydrate A ctive En Zymes ) degrade, synthesize, and modify all complex carbohydrates on Earth. CAZymes are extremely important to research in human health, nutrition, gut microbiome, bioenergy, plant disease, and global carbon recycling. Current CAZyme annotation tools are all based on sequence similarity.
View Article and Find Full Text PDFCitri reticulate pericranium-derived extracellular vesicles exert antioxidant and anti-inflammatory properties and enhance the bioactivity of nobiletin by forming EVs-nob nanoparticles.
Front Cell Dev Biol
December 2024
Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China.
Plant-driven extracellular vesicles (PEVs) have attracted significant interest due to their natural origin, remarkable bioactivity, and efficacy in drug encapsulation and target delivery. In our work, extracellular vesicles from Citri Reticulate Pericranium (CEVs) were isolated and investigated their physicochemical characteristics and biological activities. We identified the vesicle structures as regular, with a particle size of approximately 200 nm.
View Article and Find Full Text PDFEmotional Eating Interventions for Adults Living With Overweight and Obesity: A Systematic Review and Meta-Analysis of Behaviour Change Techniques.
J Hum Nutr Diet
February 2025
School of Health, Obesity Institute, Leeds Beckett University, Leeds, UK.
Background: Emotional eating (EE) is a barrier to the long-term success of weight loss interventions. Psychological interventions targeting EE have been shown to reduce EE scores and weight (kg), though the mechanisms remain unclear. This review and meta-analysis aimed to identify the specific behaviour change techniques (BCTs) associated with improved outcomes.
View Article and Find Full Text PDFA new disease symptomology observed in wheat is associated with high levels of Triticum mosaic virus transcripts.
Plant Dis
January 2025
Colorado State University System, Soil and Crop Sciences, Fort Collins, Colorado, United States;
Wheat is an important cereal crop globally and in the United States, and is the largest crop grown by acreage in Colorado. In June 2023, we observed wheat fields displaying severe yellowing and virus-like disease symptoms in plants across seven eastern Colorado counties (Yuma, Prowers, Kit Carson, Washington, Sedgewick, Morgan, and Weld). Symptomatic plants were prominent in fields and appeared bright yellow, with ringspots, mosaic patterning, and streaking on leaves.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!