There is a strong desire for sizing and identification of nanoparticles in fields of advanced nanotechnology and environmental protection. Although existing approaches can size the nanoparticles, or identify nanoparticles with different refractive indexes, a fast and simple method that combines the two functions still remains challenges. Here, we propose a versatile optical method to size and identify nanoparticles using an optical tapered fiber. By detecting reflection signals in real time, 400-600 nm SiO nanoparticles can be sized and 500 nm SiO, PMMA, PS nanoparticles can be identified. This method requires only an optical tapered fiber, avoiding the use of elaborate nanostructures and making the device highly autonomous, flexible and compact. The demonstrated method provides a potentially powerful tool for biosensing, such as identification of nano-contaminant particles and biological pathogens.
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http://dx.doi.org/10.1039/c8ra06454g | DOI Listing |
Commun Eng
December 2024
State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, China.
Rapid and accurate determination of target proteins in cells provide essential diagnostic information for early detection of diseases, evaluation of drug responses, and the study of pathophysiological mechanisms. Traditional Western blotting method has been used for the determination, but it is complex, time-consuming, and semi-quantitative. Here, a tapered seven-core fiber (TSCF) biosensor was designed and fabricated.
View Article and Find Full Text PDFRev Sci Instrum
December 2024
OFS Laboratories, 19 Schoolhouse Road, Somerset, New Jersey 08873, USA.
Transmission matrix measurements of multimode fibers are now routinely performed in numerous laboratories, enabling control of the electric field at the distal end of the fiber and paving the way for the potential application to ultrathin medical endoscopes with high resolution. The same concepts are applicable to other areas, such as space division multiplexing, targeted power delivery, fiber laser performance, and the general study of the mode coupling properties of the fiber. However, the process of building an experimental setup and developing the supporting code to measure the fiber's transmission matrix remains challenging and time consuming, with full details on experimental design, data collection, and supporting algorithms spread over multiple papers or lacking in detail.
View Article and Find Full Text PDFSci Adv
December 2024
CAS Key Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Numerous organisms exploit asymmetrical capillary forces generated by unique fiber or asymmetrical tapered structures to rapidly eliminate undesired liquid for survival in moist or rainy habitats. Human eyelashes, the primary protector of eyes, use a yet-to-be-fully-understood mechanism to efficiently transfer incoming liquid for vision safeguarding. Here, we elucidate that human eyelashes featuring a hydrophobic curved flexible fiber array with surface micro-ratchet and macro-curvature approximating the is adept at directionally and rapidly expelling incoming liquid to maintain clear vision.
View Article and Find Full Text PDFPenicillin G detection is of great significance in medical research and disease diagnosis. Liquid crystal (LC), as a branch of sensitive materials, has a broad application prospect in the field of biosensing. Herein, a liquid crystal-coated silica microbubble resonator (LC-MBR), with high sensitivity for penicillin G detection, has been proposed and demonstrated.
View Article and Find Full Text PDFSmall Methods
December 2024
State Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
Measurement of masses of microscale objects or weak force with ultrahigh sensitivity (down to nanogram/piconewton level) and compact configuration is highly desired for fundamental research and applications in various disciplines. Here, by using freestanding gold flakes with high reflectivity (≈98% at 980 nm) as the sample tray and silica microfibers with extremely low spring constant (≈0.05 mN m) as the cantilever beams, miniature capacitive balances are reported with piconewton-level detection limit (picobalances) and reliable radiation force-based calibration.
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