Objective: This study was performed to establish a quantitative evaluation and comparison of fixation stability, as measured by an eye tracker, using image-based areas determined by the bivariate contour ellipse area (BCEA), kernel density estimation (KDE), and Scanpath methods.

Methods: This prospective cross-sectional study included 45 and 20 participants with abnormal and normal phoria, respectively. Eye movements were recorded using a remote eye tracker and were plotted using RStudio software. Image-based areas were evaluated using ImageJ software.

Results: The image-based areas used to evaluate fixation stability exhibited decreasing stability in the abnormal phoria group in the following order: KDE with ±1 standard deviation (SD), BCEA with ±1 SD, KDE with ±2 SD or Scanpath, and BCEA with ±2 SD. The BCEA tended to be overestimated, and the KDE tended to be underestimated at high density. The Scanpath method had a very high probability area because the area spans all gaze points.

Conclusions: Fixation stability could be quantified as image-based areas by the KDE, BCEA, and Scanpath methods. Our findings suggest that fixation stability may be evaluated using one or more methods.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112722PMC
http://dx.doi.org/10.1177/03000605221098183DOI Listing

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