Phytochemical investigation the resins of K.M.Shen yielded three new tetrahydrobenzofuran derivatives named as A-C (). The structures of the new compounds were elucidated by analysis of their NMR, HRMS, and ECD spectra, and the absolute configurations were established through the comparison of experimental and calculated ECD spectra. Compound exhibited moderate antitumor activities against AGS cancer cell with IC values of 15.6 µM. Moreover, assays demonstrated that compound could induce AGS cancer cell apoptosis.
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