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Evaluation of RMplex system for differentiating father-son pairs using Y-STRs in a Korean population.
Forensic Sci Int Genet
January 2025
Forensic DNA Division, National Forensic Service, Wonju, South Korea. Electronic address:
Y-chromosomal short tandem repeats (Y-STRs) at rapidly mutating (RM) loci have been suggested as tools for differentiating paternally related males. RMplex is a recently developed system that incorporates 26 RM loci and four fast-mutating (FM) loci, targeting 44 male-specific loci. Here, we evaluated the RMplex by estimating Y-STR mutation rates and the overall differentiation rates for 542 Korean father-son pairs, as well as the genetic population values for 409 unrelated males.
View Article and Find Full Text PDFTrends in Mental Health Outcomes of College Students Amid the Pandemic (Roadmap mHealth App): Longitudinal Observational Study.
J Med Internet Res
January 2025
Department of Pediatrics, Medical School, University of Michigan, Ann Arbor, MI, United States.
Background: The mental health crisis among college students intensified amid the COVID-19 pandemic, suggesting an urgent need for innovative solutions to support them. Previous efforts to address mental health concerns have been constrained, often due to the underuse or shortage of services. Mobile health (mHealth) technology holds significant potential for providing resilience-building support and enhancing access to mental health care.
View Article and Find Full Text PDFApplication of 99mTc-FAPI-46 Imaging in a Patient With Medullary Thyroid Carcinoma: Navigating the Landscape of Novel Radiotracers.
Clin Nucl Med
December 2024
From the Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
We present the case of a 58-year-old man with metastatic medullary thyroid carcinoma refractory to conventional therapies, including peptide receptor radionuclide therapy. Despite multiple interventions, serum calcitonin and carcinoembryonic antigen levels continued to rise. Subsequent evaluation with 99mTc-FAPI-46 revealed remarkable uptake in metastatic lesions, suggesting a potential role for FAPI-labeled radioisotopes in the management of medullary thyroid carcinoma.
View Article and Find Full Text PDFThe acquisition of chopstick skills is considered essential for child development and etiquette in many Asian cultures. However, a decline in chopstick education has been observed in Japan, and the underlying causes of this phenomenon remain elusive. This study aims to investigate children's chopstick skills and develop an objective method to evaluate them using a hand posture estimation model.
View Article and Find Full Text PDFImpacts of variable magnetic field on ternary Casson nanofluid flow through ciliated arterial walls incorporating interfacial nanolayer.
Electromagn Biol Med
January 2025
Department of Applied Mathematics, University of Calcutta, Kolkata, India.
The current investigation explores tri-hybrid mediated blood flow through a ciliary annular model, designed to emulate an endoscopic environment. The human circulatory system, driven by the metachronal ciliary waves, is examined in this study to understand how ternary nanoparticles influence wave-like flow dynamics in the presence of interfacial nanolayers. We also analyze the effect of an induced magnetic field on Ag-Cu-/blood flow within the annulus, focusing on thermal radiation, heat sources, buoyancy forces and ciliary motion.
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