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| http://dx.doi.org/10.1021/jacs.2c04434 | DOI Listing |
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Effects of Acute Stress on Metabolic Interactions Related to the Tricarboxylic Acid (TCA) Cycle in the Left Hippocampus of Mice.
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December 2024
Department of Radiation Convergence Engineering, College of Software and Digital Healthcare Convergence, Yonsei University, 1, Yeonsedae-gil, Heungeop-myeon, Wonju 26493, Republic of Korea.
Background/objectives: The acute stress response affects brain metabolites closely linked to the tricarboxylic acid (TCA) cycle. This response involves time-dependent changes in hormones and neurotransmitters, which contribute to resilience and the ability to adapt to acute stress while maintaining homeostasis. This physiological mechanism of metabolic dynamics, combined with time-series analysis, has prompted the development of new methods to observe the relationship between TCA cycle-related brain metabolites.
View Article and Find Full Text PDFUsing Serum Metabolomic Signatures to Investigate Effects of Acupuncture on Pain-Fatigue-Sleep Disturbance in Breast Cancer Survivors.
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College of Nursing, University of Illinois Chicago, 845 S. Damen Avenue, Chicago, IL 60612, USA.
Background/objectives: Acupuncture is an efficacious integrative therapy for treating pain, fatigue, and sleep disturbance (the psychoneurological symptom cluster) in breast cancer survivors. However, the mechanisms underlying its effects remain unclear, and related metabolomics studies are limited. This study aimed to examine serum metabolite changes after acupuncture and their relationships to symptom improvement.
View Article and Find Full Text PDFAldolase B Deficient Mice Are Characterized by Hepatic Nucleotide Sugar Abnormalities.
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January 2025
Department of Internal Medicine, Division of Endocrinology and Metabolic Disease, Maastricht University Medical Center+, Maastricht, The Netherlands.
Hereditary fructose intolerance (HFI) is characterized by liver damage and a secondary defect in N-linked glycosylation due to impairment of mannose phosphate isomerase (MPI). Mannose treatment has been shown to be an effective treatment in a primary defect in MPI (i.e.
View Article and Find Full Text PDFEfficient gaze stabilization during video Active Gaze Shift Test (vAGST) in bilateral vestibulopathy.
Front Neurol
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Institut de Recherche Oto-Neurologique (IRON), Paris, France.
Introduction: While most head movements in daily life are active, most tools used to assess vestibular deficits rely on passive head movements. A single gain value is not sufficient to quantify gaze stabilization efficiency during active movements in vestibular deficit patients. Moreover, during active gaze shifts, anticipatory mechanisms come into play.
View Article and Find Full Text PDFWNT4 promotes the symmetric fission of crypt in radiation-induced intestinal epithelial regeneration.
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Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China.
Background: Radiotherapy for pelvic malignant tumors inevitably causes intestinal tissue damage. The regeneration of intestinal epithelium after radiation injury relies mainly on crypt fission. However, little is known about the regulatory mechanisms of crypt fission events.
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