Physiological Effects of Wearing N95 Respirator on Medical Staff During Prolong Work Hours in Covid-19 Departments.

J Occup Environ Med

From the Internal Medicine Department, Sheba Medical Center, Tel Hashomer, Israel (Dr Shechtman and Dr Ben-Zvi); Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (Dr Shechtman, Dr ben-Haim, Dr Ben-Zvi, Dr Steel, Dr Ironi, Dr Chatterji, and Dr Levy); Department of Emergency Medicine, Sheba Medical Center, Tel Hashomer, Israel (Dr Ben-Haim, Dr Steel, and Dr Ironi); Biostatistics Research Unit, University Health Network, University of Toronto, Toronto, ON, Canada (Dr Huszti); Institute of Pulmonary Medicine, Sheba Medical Center, Tel-Hashomer, Israel (Dr Chatterji and Dr Levy).

Published: June 2022

Objective: The objective of the current study was to determine gas exchange abnormalities and physiological changes among healthcare workers during a 4-hour emergency department (ED) shift while wearing the N95 respirator.

Methods: Single-center prospective observational study. Comparisons of paired measurements were performed using a non-parametric Wilcoxon matched-pairs signed-rank test. Results: Forty-one subjects were included. Prolonged N95 respirator use was associated with a significant decline in plasma pH (7.35 mmHg vs 7.34 mmHg, P = 0.02), PvO 2 (23.2 mmHg vs 18.6 mmHg, P < 0.001) and a concurrent increase in EtCO 2 (32.5 mmHg vs 38.5 mmHg, P < 0.0001). PvCO 2 and bicarbonate levels did not differ. No significant change was observed for heart rate or oxygen saturation.

Conclusion: Using an N95 respirator for prolonged periods by healthcare professionals may provoke changes in gas exchange. The clinical significance of these changes remains to be determined.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275795PMC
http://dx.doi.org/10.1097/JOM.0000000000002542DOI Listing

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