We herein report the functionalization of α-C-H in alcohols through cross-dehydrogenative coupling reactions. Selectfluor was used as a mild oxidant. -generated HF participated in the reaction and no external strong acid was necessary. A variety of heteroaryl-substituted alcohols were achieved with good yields and with good functional group tolerance.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076519 | PMC |
http://dx.doi.org/10.1039/c9ra09954a | DOI Listing |
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