Informal STEM learning (ISL) programs propel the connections between science and society. The STEM Advocacy Institute (SAi) is an experimental incubator that is addressing the ongoing challenges faced by founders of such initiatives. The holistic model used by the institute can be both scaled and replicated in other contexts to nurture novel ideas and projects in ISL.
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| http://dx.doi.org/10.1016/j.tcb.2022.04.003 | DOI Listing |
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Background: Achieving a stable vasculature is crucial for tissue regeneration. Endothelial cells initiate vascular morphogenesis, followed by mural cells that stabilize new vessels. This study investigated the in vivo effects of Sema4D-Plexin-B1 signaling on stem cells from human exfoliated deciduous teeth (SHED)-supported angiogenesis, focusing on its mechanism in PDGF-BB secretion.
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Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 287 Giuseppe Campi Street, 41125 Modena, Italy.
: Team-based learning is an educational strategy that promotes active learning and student engagement through structured team activities. It contrasts with traditional teaching models by emphasizing student preparation and collaboration. The TBL-SAI is a reliable and valid instrument designed to evaluate students' attitudes towards TBL, assessing dimensions such as accountability, preference for lecture or team-based learning, and satisfaction with TBL.
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Department of Nursing, School of Nursing and Midwifery, Islamic Azad University, Kazerun, Iran.
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Addition of pembrolizumab to neoadjuvant chemotherapy followed by adjuvant pembrolizumab improved outcomes in patients with high-risk, early-stage, triple-negative breast cancer. However, whether the addition of neoadjuvant pembrolizumab to chemotherapy would improve outcomes in high-risk, early-stage, estrogen receptor-positive/human epidermal growth factor receptor 2-negative (ER/HER2) breast cancer remains unclear. We conducted a double-blind, placebo-controlled phase 3 study (KEYNOTE-756) in which patients with previously untreated ER/HER2 grade 3 high-risk invasive breast cancer (T1c-2 (≥2 cm), cN1-2 or T3-4, cN0-2) were randomly assigned (1:1) to neoadjuvant pembrolizumab 200 mg or placebo Q3W given with paclitaxel QW for 12 weeks, followed by four cycles of doxorubicin or epirubicin plus cyclophosphamide Q2W or Q3W.
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Department of Biosciences, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Sri Sathya Sai District, Puttaparthi, Andhra Pradesh 515134, India.
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