Purpose: Cataract (opacification of the ocular lens) is a typical tissue reaction (deterministic effect) following ionizing radiation exposure, for which prevention dose limits have been recommended in the radiation protection system. Manifestations of radiation cataracts can vary among individuals, but such potential individual responses remain uncharacterized. Here we review relevant literature and discuss implications for radiation protection. This review assesses evidence for significant modification of radiation-induced cataractogenesis by age at exposure, sex and genetic factors based on current scientific literature.
Conclusions: In addition to obvious physical factors (e.g. dose, dose rate, radiation quality, irradiation volume), potential factors modifying individual responses for radiation cataracts include sex, age and genetics, with comorbidity and coexposures also having important roles. There are indications and preliminary data identifying such potential modifiers of radiation cataract incidence or risk, although no firm conclusions can yet be drawn. Further studies and a consensus on the evidence are needed to gain deeper insights into factors determining individual responses regarding radiation cataracts and the implications for radiation protection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09553002.2022.2074166 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
PACKMOL-GUI: An All-In-One VMD Interface for Efficient Molecular Packing.
J Chem Inf Model
January 2025
Sino-Finland Joint AI Laboratory for Child Health of Zhejiang Province, Hangzhou 310052, China.
PACKMOL is a widely utilized molecular modeling tool within the computational chemistry community. However, its tremendous advantages have been impeded by the longstanding lack of a robust open-source graphical user interface (GUI) that integrates parameter settings with the visualization of molecular and geometric constraints. To address this limitation, we have developed PACKMOL-GUI, a VMD plugin that leverages the dynamic extensibility of the Tcl/Tk toolkit.
View Article and Find Full Text PDFEfficacy of Natural β-Carotene Chewable Tablets Derived from Banana ( AA) Pulp in Reducing UV-Induced Skin Erythema.
Nutrients
December 2024
Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
Background/objectives: UV radiation is a primary cause of skin damage and photoaging. β-carotene, a potent antioxidant, aids in mitigating UV-induced oxidative stress and enhancing skin photoprotection. This research aimed to evaluate the efficacy of a nutraceutical product designed to prevent photoaging.
View Article and Find Full Text PDFAssessment of Radiological Safety of Ceramic Tiles Commonly Used in Polish Buildings.
Materials (Basel)
December 2024
Institute of Safety Engineering, Fire University, 52/54 Słowackiego St., 01-629 Warsaw, Poland.
The concentration of natural radionuclides Ra, Th and K in ceramic tiles manufactured in Poland is presented in this paper. The concentration of natural radioactive isotopes in the tested samples was determined using a low-level digital gamma ray spectrometer equipped with an HPGe semiconductor detector. The mean concentrations of Ra, Th and K in the analyzed samples were found to be 48 ± 3 Bq∙kg, 49 ± 3 Bq∙kg and 476 ± 23 Bq∙kg, respectively.
View Article and Find Full Text PDFThiosemicarbazone-Based Compounds: A Promising Scaffold for Developing Antibacterial, Antioxidant, and Anticancer Therapeutics.
Molecules
December 2024
Department of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, 90-151 Lodz, Poland.
This paper presents the synthesis and characterization of new thiosemicarbazone derivatives with potential applications as antibacterial, antioxidant and anticancer agents. Six thiosemicarbazone derivatives (L-L5) were synthesized by reacting an appropriate thiosemicarbazide derivative with 2-pyridinecarboxaldehyde. The structures of the obtained compounds were confirmed using mass spectrometry, infrared spectroscopy, and NMR spectroscopy.
View Article and Find Full Text PDFIncreasing temperature counteracts the negative effects of ultraviolet radiation on Microcystis aeruginosa under future climate scenarios in relation to physiological processes.
Comp Biochem Physiol C Toxicol Pharmacol
January 2025
Consejo Nacional de Investigaciones Científicas y Técnicas de Argentina, CABA, Argentina; Departamento de Radiobiología, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica, General San Martín, Argentina; Red de Investigación de estresores Marinos-Costeros en América Latina y el Caribe, Mar del Plata, Argentina. Electronic address:
Heat waves, are a major concern related to climate change, and are projected to increase in frequency and severity. This temperature rise causes thermal stratification, exposing surface-dwelling organisms to higher levels of ultraviolet radiation (UVR). This study aims to understand how the toxic bloom-forming cyanobacterium Microcystis aeruginosa adapts to changing climatic conditions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!