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Midbrain cholinergic neurons signal negative feedback to promote behavioral flexibility. | LitMetric

Midbrain cholinergic neurons signal negative feedback to promote behavioral flexibility.

Trends Neurosci

Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, USA. Electronic address:

Published: July 2022

Cholinergic neurons of the pedunculopontine nucleus (PPN) are relevant for adaptive behavior. In a recent study, Ruan et al. revealed that PPN cholinergic neurons signal negative feedback during reward omission after contingency changes, which is necessary for switching to new behavioral strategies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635055PMC
http://dx.doi.org/10.1016/j.tins.2022.04.005DOI Listing

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