Adalimumab-Induced Psoriasis with Severe Alopecia.

Skinmed

Division of Dermatology, Faculty of Medicine, Lebanese University, Beirut, Lebanon;

Published: May 2022

AI Article Synopsis

  • A 52-year-old woman with a history of Crohn's disease and arthritis experienced severe hair loss after starting treatment with adalimumab.
  • She developed pustular lesions on her palms, soles, and scalp, leading to the discontinuation of adalimumab and a switch to ustekinumab injections.
  • After two months of ustekinumab, she sought treatment at a dermatology clinic for her ongoing alopecia, noting she had no personal or family history of psoriasis.

Article Abstract

A 52-year-old woman with a 10-pack-year smoking history presented with serious hair loss. She had a 10-year history of Crohn's disease associated with arthritis, for which she had been taking adalimumab. After 2 months of this treatment, she developed pustular lesions on her palms, soles, and scalp. Her gastroenterologist discontinued adalimumab injections, ordered skin biopsy, and switched her to ustekinumab 90-mg subcutaneous injections every 8 weeks. She then presented to our dermatology clinic, 2 months following the initiation of anti-IL12/23 medications, for her alopecia. She had no personal or family history of psoriasis. (. 2022;20:136-138).

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