A 39-year-old female presented with complaints of occipital headaches, diplopia, numbness over left half of face and deviation of face to the right. On examination she had hypoesthesia over left half of face, associated with bilateral abductor and left facial palsy. Neuroradiology showed a well-defined lytic lesion involving the clivus and adjacent sphenoid sinus and sella. The patient underwent an endoscopic transnasal decompression of the clival lesion. Intraoperative squash preparation was reported to show tuberculous granulation, which was confirmed on postoperative histology. The patient was advised anti-tubercular therapy. At 12 months follow up neuroradiology showed a near total resolution of the clival lesion. The patient had completely recovered from her cranial nerve deficits. Tuberculous involvement of spheno-clival region is rare and the authors' literature search has yielded only three previous similar case reports. A surgical decompression followed by anti-tubercular therapy is the recommended approach for management of clival tuberculosis. The relevant literature on the subject is presented.
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http://dx.doi.org/10.4103/0028-3886.344665 | DOI Listing |
Neurol India
May 2022
Department of Neurosurgery, BYL Nair Ch. Hospital and Topiwala National Medical College, Mumbai, Maharashtra, India.
A 39-year-old female presented with complaints of occipital headaches, diplopia, numbness over left half of face and deviation of face to the right. On examination she had hypoesthesia over left half of face, associated with bilateral abductor and left facial palsy. Neuroradiology showed a well-defined lytic lesion involving the clivus and adjacent sphenoid sinus and sella.
View Article and Find Full Text PDFJ Clin Tuberc Other Mycobact Dis
December 2021
Division of Infection, Royal London Hospital, Barts Health NHS Trust, London, United Kingdom.
Herein we report a 30-year-old man presenting with fevers, headaches and weight loss. On admission he was disorientated and demonstrated no focal signs of neurological deficit. Magnetic resonance imaging revealed a large area of abnormal bone marrow signal centred within the clivus with extension into the sphenoid sinus and signs of associated basal meningitis.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
November 2019
Department of Otorhinolaryngology, Head & Neck Surgery, All India Institute of Medical Sciences, 4065, ENT Office, 4th Floor, Teaching Block, New Delhi, India.
The increase awareness and advent of anti-tuberculosis therapy led to decline in tuberculosis. Now a resurgence of tuberculosis is with immunosuppression and with resistant strains. The detection rate of extrapulmonary is increased with the advent of newer modalities of detection, imaging, and better testing.
View Article and Find Full Text PDFPediatr Neurosurg
October 2018
Department of Neurosurgery, NIMHANS, Bangalore, India.
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