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Pericardial Effusion during Proton Therapy in a Patient with Chemorefractory Hodgkin Lymphoma. | LitMetric

AI Article Synopsis

  • A 24-year-old female undergoing proton therapy for classical Hodgkin lymphoma experienced recurrent pericardial effusion, an uncommon event during active radiation treatment.
  • Pericardial effusion usually occurs as a result of lymphoma or as a late side effect of radiotherapy, but this case highlights the rarity of it occurring concurrently with treatment.
  • Proper identification and management of pericardial effusion during radiation therapy is crucial, as it can impact radiation dosimetry and overall patient outcomes.

Article Abstract

We present a case of recurrent pericardial effusion presenting during proton therapy in a 24-year-old female receiving mediastinal treatment for classical Hodgkin lymphoma. Pericardial effusion is typically considered an event accompanying lymphoma diagnosis or as a subacute or late effect of radiotherapy. Rarely has it been described as occurring during radiation treatment with photon-based radiotherapy, let alone proton therapy. It is unclear what underlying cause triggered recurrent effusion in this patient. Identifying and managing pericardial effusion during treatment delivery is important to consider as it may affect radiation dosimetry, particularly with proton therapy. Doing so will help ensure patients receive optimal treatment and minimize the risks of morbidity and mortality.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009456PMC
http://dx.doi.org/10.14338/IJPT-21-00010DOI Listing

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