Mastitis is the most important disease in dairy cattle industry because of its high economic losses both in herd management, milk and milk products. The aim of this study was to determine the efficacy of inactivated (IPPVO) Para immune activator as a prophylaxis against mastitis and as the therapy for subclinical mastitis in dairy cattle. The prophylactic effects of IPPVO were investigated in California mastitis test (CMT). Healthy Holstein cows were divided into A1 (n = 30) and A2 (n = 30) subgroups. In addition, 90 subclinical mastitis Holstein cows were divided into subgroups of B1, B2, and B3 to investigate the efficacy of IPPVO treatment. A significant difference in CMT levels was observed ( ˂ 0.01) 30 day after treatment in A groups. The difference in somatic cell count (SCC) levels between the A groups 15, 30 day after treatment was significant ( ˂ 0.01). The results of the CMT among the B groups showed no statistically significant difference ( > 0.05). The results of the SCC tests showed no statistically significant difference ( > 0.05) among the B groups on days 0, 9 and 15 after treatment. Coagulase-negative (n = 53) and (n = 30) were the most prevalent bacteria isolated in this study. In conclusion, IPPVO, although had no additional effect when used in combination with antibiotics could possibly be used instead of antibiotics and to protect cattle from subclinical mastitis, however, it is not known how long this prophylaxis effect could last.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010833 | PMC |
| http://dx.doi.org/10.30466/vrf.2019.110810.2628 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mapping Antimicrobial Resistance in Isolates from Subclinical Mastitis in Danish Dairy Cows.
Antibiotics (Basel)
January 2025
SEGES Innovation P/S, Agro Food Park, 8200 Aarhus, Denmark.
Although is a key cause of subclinical mastitis in Danish dairy cows, its sensitivity to antimicrobials remains unexplored. Here, we analyzed sixty isolates derived from 42 dairy cows across six conventional dairy herds in Denmark. Phenotypic resistance was measured by antimicrobial susceptibility testing and minimum inhibitory concentration (MIC) analysis, and genotypic resistance was examined through whole-genome sequencing and identification of antimicrobial resistance genes (ARGs).
View Article and Find Full Text PDFA Prospective Study of the Prevalence and Predictive Risk Factors of Repeat Breeder Syndrome in Dairy Cattle in the North of Spain.
Animals (Basel)
January 2025
Unit of Reproduction and Obstetrics, Department of Animal Pathology, Faculty of Veterinary Medicine, Universidade de Santiago de Compostela (USC), 27002 Lugo, Spain.
This study examined the prevalence and risk factors of repeat breeder syndrome (RB) in 2370 dairy cows in northern Spain. Data collected included the prevalence of postpartum pathologies, metabolic markers, and productive and reproductive parameters. The overall RB prevalence was 21.
View Article and Find Full Text PDFPrevalence and Zoonotic Risk of Multidrug-Resistant in Bovine Subclinical Mastitis Milk: Insights Into the Virulence and Antimicrobial Resistance.
Food Sci Nutr
January 2025
Department of Dairy Science, Faculty of Veterinary, Animal and Biomedical Sciences Sylhet Agricultural University Sylhet Bangladesh.
The emergence of antibiotic-resistant microorganisms has made antimicrobial resistance a global issue, and milk is a potential source for the propagation of resistant bacteria causing zoonotic diseases. Subclinical mastitis (SCM) cases, often overlooked and mixed with normal milk in dairy farms, frequently involve , which can spread through contaminated milk. We conducted this study to determine the prevalence of virulence genes, antibiotic resistance genes (ARGs), antimicrobial susceptibility, and the genetic relatedness of multidrug-resistant (MDR) Shiga toxin-producing (STEC) isolated from SCM milk.
View Article and Find Full Text PDFPrevalence, antimicrobial susceptibility profiles and resistant gene identification of bovine subclinical mastitis pathogens in Bangladesh.
Heliyon
July 2024
Department of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.
Subclinical mastitis (SCM), a silent threat in the dairy sector of Bangladesh poses a significant economic impact and serves as a potential source of infection for healthy cows, hindering efforts to achieve milk self-sufficiency. Despite the importance of this issue, limited research has been conducted on mastitis in Sylhet region of Bangladesh. This study aimed to investigate the molecular prevalence, antimicrobial susceptibility profile and resistant genes detection on pathogens ( and causing SCM.
View Article and Find Full Text PDFOur research on the expression and characterization of exosomal miRNAs in buffalo milk, particularly in the context of healthy, sub-clinical mastitis and pasteurized milk, is a novel contribution to the field. We are the first to investigate the expressions of miRNAs and the characterization of exosomes in boiled and pasteurized milk. This study is based on clinical signs and CMT, where twenty buffalo milk samples were divided into normal and sub-clinical mastitis and a third group of ten commercial pasteurized milk.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!