A solvent extract of the soft coral afforded cembrene diterpenoids, sarcoehrenbergilid D-F (1-3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1-3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070672 | PMC |
http://dx.doi.org/10.1039/c9ra04158c | DOI Listing |
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