Ultrathin nickel-metal-organic framework nanobelt based electrochemical sensor for the determination of urea in human body fluids.

RSC Adv

Key Laboratory of Magnetic Molecules and Magnetic Information Materials (Ministry of Education), School of Chemistry and Material Science, Shanxi Normal University Linfen 041004 China +86-357-2051192 +86-357-2051192.

Published: September 2019

Ultrathin nickel-metal-organic framework (Ni-MOF) nanobelts, [Ni(CHO)(HO)]·40HO (Ni-MIL-77), have been exploited successfully for the fabrication of a non-enzymatic urea sensor. Ni-MOF ultrathin nanobelts in alkaline media can be used as an efficient catalyst for urea electrooxidation. As a non-enzymatic urea sensor, Ni-MOF ultrathin nanobelts exhibit a high sensitivity of 118.77 μA mM cm, wide linear range of 0.01-7.0 mM, and low detection limit of 2.23 μM (S/N = 3). The selectivity, stability and reliability of ultrathin Ni-MOF nanobelts towards urea oxidation are also investigated. Moreover, Ni-MOF ultrathin nanobelts were further used to detect urea in human body fluids. All these findings confirm that the urea sensor based on Ni-MOF ultrathin nanobelts is successfully prepared and promising for applications in medical diagnostics and environmental monitoring.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9071849PMC
http://dx.doi.org/10.1039/c9ra05716aDOI Listing

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