A simple, mild and efficient protocol was developed for the alkylation of fluorene with alcohols in the presence of -BuOK as catalyst, affording the desired 9-monoalkylfluorenes with near quantitative yields in most cases.
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http://dx.doi.org/10.1039/c9ra07557g | DOI Listing |
Asian Pac J Cancer Prev
December 2024
Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background And Objective: Hepatocellular carcinoma (HCC) is recognized as one of the major public health problems and deadly malignancies worldwide. Today, the use of compounds of natural origin in the treatment of cancer and other diseases has been of interest to researchers. Marine compounds such as algae have anti-cancer effects.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
October 2024
Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Objective: Hepatocellular carcinoma (HCC) is a significant type of liver cancer. In spite of many treatment approaches, its treatment is still associated with challenges. Therefore, new approaches with minimal side effects are necessary for its treatment.
View Article and Find Full Text PDFLangmuir
November 2024
Organic and Bioorganic Chemistry Laboratory, Council of Scientific and Industrial Research (CSIR) - Central Leather Research Institute (CLRI), Adyar, Chennai 600020, India.
Sci Rep
October 2024
Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Rd, Ratchathewi, Bangkok, 10400, Thailand.
Developing cost-effective, high-efficiency, and stable hole transporting materials (HTMs) is crucial for replacing traditional spiro-OMeTAD in perovskite solar cells (PSCs) and achieving sustainable solar energy solutions. This work presents two novel air-stable HTMs based on a spiro[fluorene-9,9'-xanthene] (SFX) core functionalized with N-methylcarbazole (XC2-M) and N-hexylcarbazole (XC2-H) rings. These HTMs were synthesized via a straightforward, three-step process with good overall yields (∼40%) and low production costs.
View Article and Find Full Text PDFChem Asian J
January 2025
Department of Chemistry, National Institute of Technology Calicut, 673601, Kozhikode, Kerala, India.
Herein, we report an inexpensive first-row transition metal Ni heterogeneous catalytic system for the C -mono alkylation of fluorene using alcohols as alkylating agents via borrowing hydrogen strategy. The catalytic protocol displayed versatility with high yields of the desired products using various types of primary alcohols, including aryl/hetero aryl methanols, and aliphatic alcohols as alkylating agents. The catalyst Ni NPs@N-C was synthesized via high-temperature pyrolysis strategy, using ZIF-8 as the sacrificial template.
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