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Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases. | LitMetric
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Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases.

Rodrigo Boscariol José M Oliveira Junior Denicezar A Baldo Victor M Balcão Marta M D C Vila

Saudi Pharm J

PhageLab - Laboratory of Biofilms and Bacteriophages, University of Sorocaba, 18023-000 Sorocaba, SP, Brazil.

Published: April 2022

The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases. An in-depth analysis of the effect of CAGE-IL concentration in the enhancement of transdermal permeation of curcumin was performed, and the results were modelled via nonlinear regression analysis. The results obtained showed that a low percentage of CAGE-IL (viz. 2.0%, w/w) was effective in disrupting the skin structure in a transient fashion, facilitating the passage of curcumin dissolved in it.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068761PMC
http://dx.doi.org/10.1016/j.jsps.2022.01.023DOI Listing

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