AI Article Synopsis
- Asymptomatic children can transmit Group A Streptococcus (GAS), posing a risk for acute rheumatic fever in those susceptible.
- A study in Jakarta investigated how common GAS carriers are among 201 asymptomatic schoolchildren and analyzed their antibiotic sensitivity.
- Results showed a 13.9% carrier rate, with tonsillar enlargement being a predictor, and GAS remaining largely sensitive to penicillin and erythromycin but showing increased resistance to tetracycline.
Article Abstract
Introduction: Transmission of Group A from asymptomatic children to their surrounding carries a risk of acute rheumatic fever in susceptible people.
Aim And Objectives: We aimed to investigate the prevalence and predictors of GAS carrier state and evaluate the antibiotic sensitivity pattern of GAS in Jakarta, Indonesia.
Material And Methods: We enrolled 201 asymptomatic schoolchildren (6-12 years) using stratified random sampling from a primary school in Jakarta. None of the children had a history of rheumatic fever or rheumatic heart disease. All participants underwent physical examination, and laboratory tests include complete blood count, erythrocyte sedimentation rate, C-reactive protein, antistreptolysin O titer, and throat swab culture.
Results: The prevalence of GAS carrier was 13.9% (95% confidence interval: 9.2%-18.6%) in our study. On multivariate analysis, tonsillar enlargement was found to be the only predicting factor of GAS carrier ( = 0.03). GAS was sensitive to penicillin G, erythromycin, vancomycin, clindamycin, chloramphenicol, azithromycin, and tetracycline in 100%, 89%, 86%, 75%, 68%, 68%, and 32% of patients, respectively.
Conclusion: The GAS carrier state is common among school-age children affecting approximately 13.9% children. Tonsillar enlargement is a significant finding predictive of GAS carrier state. All isolates are still sensitive to penicillin and mostly sensitive to erythromycin but are increasingly resistant to tetracycline.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9075561 | PMC |
| http://dx.doi.org/10.4103/apc.apc_280_20 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MXene-based composite photocatalysts for efficient degradation of antibiotics in wastewater.
Sci Rep
December 2024
Department of Nano-Chemical Engineering, Faculty of Advanced Technologies, Shiraz University, Shiraz, Iran.
MXene-based (nano)materials have recently emerged as promising solutions for antibiotic photodegradation from aquatic environments, yet they are limited by scalability, stability, and selectivity challenges in practical settings. We formulated FeO-SiO/MXene ternary nano-photocomposites via coupled wet impregnation and sonochemistry approach for optimised tetracycline (TC) removal (the second most used antibiotic worldwide) from water using response surface methodology-central composite design (RSM-CCD). The photocatalysts containing various loading of FeO/SiO (5-45 wt%) on the MXene with a range of calcination temperatures (300-600 °C) via RSM optimisation were synthesised, characterised regarding crystallinity properties, surface morphology, binding energy, and light absorption capability, and analysed for TC degradation efficiency.
View Article and Find Full Text PDF[Effects of seed carrier-immobilized microorganisms on the growth of rapeseed and the remediation of petroleum hydrocarbon contaminated soil].
Ying Yong Sheng Tai Xue Bao
October 2024
School of Ecological Technology and Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
Petroleum hydrocarbon pollutants in soil are challenging to biodegrade, negatively impacting plant growth as well as the metabolic activity and community structure of soil microorganisms. Microorganisms immobilized by seed carriers can synergistically contribute to the remediation of petroleum hydrocarbon-contaminated soil. We prepared a rape seed carrier with immobilized microorganism by seed coating (with a mixture of diatomaceous earth and bentonite as fillers) and microbial immobilization.
View Article and Find Full Text PDFinvestigations on hydrodynamic phonon transport: From diffusion to convection.
Int J Heat Mass Transf
March 2024
Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, CA 90095, United States of America.
In classical theory, heat conduction in solids is regarded as a diffusion process driven by a temperature gradient, whereas fluid transport is understood as convection process involving the bulk motion of the liquid or gas. In the framework of theory, which is directly built upon quantum mechanics without relying on measured parameters or phenomenological models, we observed and investigated the fluid-like convective transport of energy carriers in solid heat conduction. Thermal transport, carried by phonons, is simulated in graphite by solving the Boltzmann transport equation using a Monte Carlo algorithm.
View Article and Find Full Text PDFA SIFT Study of Reactions of Positive and Negative Ions With Polyfluoroalkyl (PFAS) Molecules in Dry and Humid Nitrogen at 393 K.
Rapid Commun Mass Spectrom
March 2025
J Heyrovský Institute of Physical Chemistry of the CAS, Prague 8, Czechia.
Rationale: Data are required for SIFT-MS analysis of perfluoroalkyl and polyfluoroalkyl substances (PFAS), which are persistent in the environment and cause adverse health effects. Specifically, the rate coefficients and product ion branching ratios of the reactions of HO, NO, O •, O•, OH, O •, NO and NO with PFAS vapours are needed.
Methods: The dual polarity SIFT-MS instrument (Voice200) was used to generate these eight reagent ions and inject them into the flow tube with N carrier gas at a temperature of 393 K.
Light-Directed Self-Powered Metal-Organic Framework Based Nanorobots for Deep Tumor Penetration.
Adv Mater
December 2024
Frontiers Science Centre for High Energy Material, Advanced Technology Research Institute (Jinan), Key Laboratory of Cluster Science (Ministry of Education), Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, Advanced Research Institute of Multidisciplinary Science, School of Medical Technology, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China.
Effective intratumoral distribution of anticancer agents with good tumor penetration is of great practical importance for oncotherapy. How to break the limitation of traditional passive drug delivery relying on blood circulatory system into solid tumors remains a challenge. Herein, a light-directed self-powered nanorobot based on zirconium-based porphyrin metal-organic framework (MOF) is reported for smart delivery of chemodrug and photosensitizer for deep tumor penetration.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!