An analysis of myc-specific protein (p58myc), precipitated from cells transformed by virus OK10, by means of two-dimensional gel electrophoresis revealed the presence of two variants of p58myc differing in their isoelectric point. Both variants are completely cleaved by protease p15 as is the c-myc gene product precipitated from 16Q cells. The cleavage fragments of c-myc and v-myc protein do not differ in size but differ in their stability.
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