Objective: Obesity is a key factor for stress urinary incontinence. Our aim was to evaluate the long-term, subjective surgical satisfaction rate among obese (BMI ≥ 30) women after mid-urethral sling (MUS) procedure in a tertiary-level university hospital.
Study Design: This retrospective, case-control study compared the outcomes of obese and non-obese patients who underwent MUS surgery for stress urinary incontinence (SUI), March 2014-January 2020. Patients were followed-up using Urogenital Distress Inventory-6 (UDI-6) and Patient Global Impression of Improvement (PGI-I) telephone questionnaires.
Results: Among 264 patients who had MUS surgery, 107 (40.6%) patients with BMI ≥ 30 kg/m were matched with 157 (59.4%) non-obese patients (BMI < 30 kg/m). Mean follow-up was 41.4 (8-73) months. Obese women had higher post-operative urinary symptom scores in UDI-6 (32.3 vs. 25.7, p =.015) and PGI-I questionnaires (2.9 ± 1.7 vs. 2.3 ± 1.7, p =.03). More patients in the obese group (p =.03) had urinary stress symptoms. Subjective failures (PGI-I ≥ 4) totaled 46 (17.4%), 18 in obese and 28 in non-obese patients, giving cure rates of 83.2% and 82.2%, respectively (p = 1).
Conclusion: Although obese patients had higher UDI-6 scores, an interpretation of this score did not show an increase in distress due to urinary incontinence symptoms (>33.33 points).
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http://dx.doi.org/10.1016/j.ejogrb.2022.04.020 | DOI Listing |
Background: Obesity is a prevalent comorbid condition that doubles the risk of Alzheimer's disease. The proposed mechanisms underlying neuronal damage involve chronic low-grade inflammation, the production of reactive oxidative species, and altered brain glucose metabolism. In Alzheimer's disease, amyloid is thought to influence tau deposition and glucose metabolism.
View Article and Find Full Text PDFBackground: Antidepressant drug treatment may be associated with weight gain, but long-term studies are lacking.
Methods: We included 3,127 adults (1,701 women) from the REGICOR study, aged 55.6 (SD = 11.
Am J Gastroenterol
January 2025
Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Background: Hindgut symptoms are poorly understood complications of obesity. The impact of obesity on fecal incontinence (FI) and anorectal physiology remains unclear, with inconsistent results in prior studies. We aimed to evaluate the relationship between obesity and FI, and the physiological changes in anorectal function.
View Article and Find Full Text PDFMedicina (Kaunas)
November 2024
Division of Medical Oncology, Department of Internal Medicine, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul 34098, Turkey.
: Obesity is a significant risk factor for the development of breast cancer (BC) and associated poorer outcomes. A pathological complete response (pCR) with neoadjuvant chemotherapy (NACT) correlates with improved long-term prognosis in BC patients. In this study, we aimed to investigate the predictive effect of obesity on achieving pCR following NACT.
View Article and Find Full Text PDFJ Clin Med
December 2024
Bio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Previous studies showed that, paradoxically, obese patients with heart failure (HF) have better clinical outcomes compared to overweight, normal, or underweight patients. Scientific societies emphasize the importance of integrating quality of life (QoL) assessment in cardiovascular care. However, the association between QoL and weight remains understudied.
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