Large-scale distributed networks and cerebral hemispheres.

Cortex

Institute of Psychology, University of Tartu, Tartu, Estonia; National Institute for Health Development, Tallinn, Estonia.

Published: July 2022

AI Article Synopsis

  • The Central Executive Network (CEN) and Default Mode Network (DMN) are two significant large-scale brain networks that haven't been fully explored in relation to hemispheric specialization.
  • Research indicates that these networks are neuroanatomically asymmetric, with the CEN larger in the right hemisphere and the DMN larger in the left hemisphere.
  • The study suggests that this anatomical difference may indicate functional asymmetry, which could enhance our understanding of how the brain's hemispheres specialize in different tasks.

Article Abstract

The two main large-scale distributed networks, Central Executive (CEN) and Default Mode (DMN) have been extensively studied, but their relationship to hemispheric specialization has not been comprehensively addressed. We present evidence that they are neuroanatomically asymmetric: the CEN components are volumetrically larger in the right hemisphere, and DMN components are volumetrically larger in the left hemisphere. Based on this, the possibility that CEN and DMN are also functionally asymmetric is introduced and implications of the putative functional asymmetry of large-scale distributed networks for refining our understanding of hemispheric specialization are examined.

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http://dx.doi.org/10.1016/j.cortex.2022.03.010DOI Listing

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