[A spatial localization model of mobile robot based on entorhinal-hippocampal cognitive mechanism in rat brain].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi

Faculty of Information Technology, Beijing Key Laboratory of Computational Intelligence and Intelligent System, Beijing University of Technology, Beijing 100124, P. R. China.

Published: April 2022

Physiological studies reveal that rats rely on multiple spatial cells for spatial navigation and memory. In this paper, we investigated the firing mechanism of spatial cells within the entorhinal-hippocampal structure of the rat brain and proposed a spatial localization model for mobile robot. Its characteristics were as follows: on the basis of the information transmission model from grid cells to place cells, the neural network model of place cells interaction was introduced to obtain the place cell plate with a single-peaked excitatory activity package. Then the solution to the robot's position was achieved by establishing a transformation relationship between the position of the excitatory activity package on the place cell plate and the robot's position in the physical environment. In this paper, simulation experiments and physical experiments were designed to verify the model. The experimental results showed that compared with RatSLAM and the model of grid cells to place cells, the positioning performance of the model in this paper was more accurate, and the cumulative error in the long-time path integration process of the robot was also smaller. The research results of this paper lay a foundation for the robot navigation method that mimics the cognitive mechanism of rat brain.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927332PMC
http://dx.doi.org/10.7507/1001-5515.202109051DOI Listing

Publication Analysis

Top Keywords

place cells
12
spatial localization
8
localization model
8
model mobile
8
mobile robot
8
cognitive mechanism
8
mechanism rat
8
spatial cells
8
rat brain
8
model grid
8

Similar Publications

Current models for the study of neuroendocrine tumours (NETs) are severely limited. While (e.g.

View Article and Find Full Text PDF

Dentistry still faces difficulties in diagnosing oral precancer and cancer, especially when it comes to early phase changes or disease detection, evaluation, and treatment. In essence, oral lumenography is the process of identifying oral lesions using a chemiluminescent light source and a toluidine blue labeling system. Since neoplastic epithelial cells have a changed nuclear-cytoplasmic ratio, acetic acid dehydration brings out this nuclear density and gives the tissue an "acetowhite" look.

View Article and Find Full Text PDF

Microchimerism is defined as the presence of a small population of genetically distinct cells within a host that is derived from another individual. Throughout pregnancy, maternal and fetal cells are known to traffic across the feto-maternal interface and result in maternal and fetal microchimerism, respectively. However, the routes of cell transfer, the molecular signaling as well as the timing in which trafficking takes place are still not completely understood.

View Article and Find Full Text PDF

Interaction with host cell receptors initiates internalization of Kaposi's sarcoma-associated herpesvirus (KSHV) particles. Fusion of viral and host cell membranes, which is followed by release of the viral capsid into the cytoplasm, is executed by the core fusion machinery composed of glycoproteins H (gH), L (gL), and B (gB), that is common to all herpesviruses. KSHV infection has been shown to be sensitive to inhibitors of vacuolar acidification, suggestive of low pH as a fusion trigger.

View Article and Find Full Text PDF

Optimization of a micro-scale air-liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2.

Respir Res

January 2025

Department of Pediatrics, David Geffen School of Medicine, UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, UCLA, Los Angeles, CA, 90095, USA.

Background: Many respiratory viruses attack the airway epithelium and cause a wide spectrum of diseases for which we have limited therapies. To date, a few primary human stem cell-based models of the proximal airway have been reported for drug discovery but scaling them up to a higher throughput platform remains a significant challenge. As a result, most of the drug screening assays for respiratory viruses are performed on commercial cell line-based 2D cultures that provide limited translational ability.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!