YTH proteins utilize YTH domains to interact with N6-methyladenines (mA); however, Li et al. (2022) show that YTHDC2 binds U-rich motifs instead and functions independently of mA through its unusual DExD helicase domain during spermatogenesis in mice and fish.
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| http://dx.doi.org/10.1016/j.molcel.2022.04.012 | DOI Listing |
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