Susan Cheng is a clinical cardiologist, statistically trained epidemiologist, faculty mentor, and director of programs in cardiovascular population sciences, healthy aging, and public health research. In this Q&A, she shares her academic journey, current research activities, mentoring, and future directions with Cell Reports Medicine.
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| http://dx.doi.org/10.1016/j.xcrm.2022.100596 | DOI Listing |
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Science
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Center for Pulmonary Vascular Biology and Medicine, Pittsburgh, Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Vascular inflammation regulates endothelial pathophenotypes, particularly in pulmonary arterial hypertension (PAH). Dysregulated lysosomal activity and cholesterol metabolism activate pathogenic inflammation, but their relevance to PAH is unclear. Nuclear receptor coactivator 7 () deficiency in endothelium produced an oxysterol and bile acid signature through lysosomal dysregulation, promoting endothelial pathophenotypes.
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Diabetes Care
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Department of Medicine, University of California San Diego, La Jolla, CA.
Objective: Plasma metabolite profiling has uncovered several nonglycemic markers of incident type 2 diabetes (T2D). We investigated whether such biomarkers provide information about specific aspects of T2D etiology, such as impaired fasting glucose and impaired glucose tolerance, and whether their association with T2D risk varies by race.
Research Design And Methods: Untargeted plasma metabolite profiling was performed of participants in the FINRISK 2002 cohort (n = 7,564).
Terminology in ecology and evolutionary biology disproportionately harms marginalized groups.
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January 2025
Department of Forest and Conservation Sciences, Department of Botany, University of British Columbia, Vancouver, Canada.
The discipline of ecology and evolutionary biology (EEB) has long grappled with issues of inclusivity and representation, particularly for individuals with systematically excluded and marginalized backgrounds or identities. For example, significant representation disparities still persist that disproportionately affect women and gender minorities; Black, Indigenous, and People of Color (BIPOC); individuals with disabilities; and people who are LGBTQIA+. Recent calls for action have urged the EEB community to directly address issues of representation, inclusion, justice, and equity.
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View Article and Find Full Text PDFAutomated Evaluation for Pericardial Effusion and Cardiac Tamponade with Echocardiographic Artificial Intelligence.
medRxiv
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Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Background: Timely and accurate detection of pericardial effusion and assessment cardiac tamponade remain challenging and highly operator dependent.
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