The recent COVID-19 pandemic resulted in major postharvest losses because most fresh produce could not be sold. Drying is an important thermal-based food preservation method which could have prolonged the shelf-life of these produce, but most drying technologies are costly, and cannot be afforded by small-time farmers. From this context, we were interested in evaluating the drying of leaves (MOL) using a low-cost self-built prototype convective-air dryer (CAD), alongside conventional drying methods for its antioxidant properties, microbial load and phytoconstituents. Results showed total polyphenol content was the highest (p < 0.05) in our CAD samples, and it retained among the highest total flavonoid content, total antioxidant capacity, total alkaloid content and DPPH radical scavenging activity. Furthermore, methanolic CAD extract presented lower coliform and yeast and mold count than the aqueous CAD extract. We also briefly explored MOL as a sanitizer where the microbial load of the methanolic extract was comparable (p > 0.05) with several commercial non-alcoholic sanitizers, indicating its commercialization potential as a bio-friendly sanitizer. Finally, using GC-MS, we are the first to report (best of our knowledge) on the presence of caprolactam, an important bio-medical field compound, in the CAD sample's aqueous extract.
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http://dx.doi.org/10.1016/j.sjbs.2022.103290 | DOI Listing |
Breast Cancer Res
December 2024
Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22908, USA.
Background: Primary luminal breast cancer cells lose their identity rapidly in standard tissue culture, which is problematic for testing hormone interventions and molecular pathways specific to the luminal subtype. Breast cancer organoids are thought to retain tumor characteristics better, but long-term viability of luminal-subtype cases is a persistent challenge. Our goal was to adapt short-term organoids of luminal breast cancer for parallel testing of genetic and pharmacologic perturbations.
View Article and Find Full Text PDFIn Vivo
December 2024
Laboratory of Veterinary Ophthalmology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic for Korea
Background/aim: Diabetic retinopathy (DR), a complication of diabetes, causes damage to retinal blood vessels and can lead to vision impairment. Persistent high blood glucose levels contribute to this damage, and despite ongoing research, effective treatment options for DR remain limited. Dimethyl sulfoxide (DMSO) has shown anti-inflammatory and antioxidant properties in both in vivo and in vitro studies; however, its potential as an anti-inflammatory agent in the context of DR has not yet been explored.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Food Engineering and Bioprocess Technology Program, Department of Food, Agriculture, and Bioresources, School of Environment, Resources, and Development, Asian Institute of Technology, Khlong Luang, Pathumthani 12120, Thailand. Electronic address:
This research investigates the impact of microwave power, processing time, and solid-to-solvent ratio on protein recovery from foxtail millet (Setaria italica), using an artificial neural network (ANN) and genetic algorithm (GA). The extracted protein and subsequent hydrolysates were also evaluated for their techno-functional, structural, and digestibility properties. The ANN model, trained with the Levenberg-Marquardt algorithm and optimized by a GA, identified optimal extraction conditions (960 W, 66.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Pharmacy, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, PR China. Electronic address:
Gracilaria/Gracilariopsis lemaneiformis is an ecologically and economically valuable seaweed that has attracted attention for its unique flavour and rich nutritional content. Studies have shown that G. lemaneiformis contains a variety of chemical components, among which G.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address:
The pervasive use of petroleum-based food packaging has caused significant ecological damage due to their unsustainability and non-biodegradability. Polysaccharide-based biodegradable materials are promising alternatives, but low hydrophobicity and functional properties limit their practical applications which can be overcome by incorporation of phytochemical(s). Therefore, by leveraging the strong antioxidant and antibacterial potential of pterostilbene (PTB), we have developed PTB nanoemulsion (NE) incorporated chitosan/sodium alginate (CS/SA) film for food packaging applications.
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