AI Article Synopsis
- A Schiff-base ligand called 2-hydroxy-1-naphthaldehyde semicarbazone (HNS) was created and analyzed as a sensor for aluminum (Al) and fluoride (F) ions.
- HNS displays a fluorescence "turn on" effect in the presence of Al, making it useful for detecting this metal in water.
- The Al-HNS complex can also sense F ions through a metal displacement method, allowing for detection of both ions with high sensitivity and selectivity, tested successfully in living cells.
Article Abstract
A simple Schiff-base ligand 2-hydroxy-1-naphthaldehyde semicarbazone (HNS) was synthesized and characterized. Based on the combined effect of inhibition of CH[double bond, length as m-dash]N isomerization and chelation-enhanced fluorescence (CHEF), HNS functions as a fluorescence "turn on" sensor for Al in buffered aqueous media. Based on the strong affinity of Al to F ions, the generated Al-HNS complex can also be utilized as an effective chemosensor for F sensing by metal displacement approach, ensuing quenching of fluorescence by the reversible return of HNS from Al-HNS complex. Thus a method using a single probe for the detection of both Al and F ions is developed. The system exhibits high selectivity and sensitivity for Al and F ions and the detection limits were found to be as low as 6.75 × 10 M and 7.89 × 10 M, respectively. Furthermore, the practical applicability of this probe has been examined in living cells.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054392 | PMC |
| http://dx.doi.org/10.1039/d0ra02848g | DOI Listing |
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