An efficient protocol for the hydroboration of imines is reported. Lithium halide salts are effective catalysts to convert aldimines and ketimines to their corresponding amines. Here, we report excellent isolated yield of secondary amines (>95%) using 3 mol% lithium bromide in THF at room temperature. In addition, DFT calculations for a plausible reaction pathway are reported.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056805 | PMC |
| http://dx.doi.org/10.1039/d0ra06023b | DOI Listing |
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