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Zonulopathies as Genetic Disorders of the Extracellular Matrix.
Genes (Basel)
December 2024
Department of Ophthalmology, Southend University Hospital, Southend-on-Sea SS0 0RY, UK.
The zonular fibres are formed primarily of fibrillin-1, a large extracellular matrix (ECM) glycoprotein, and also contain other constituents such as LTBP-2, ADAMTSL6, MFAP-2 and EMILIN-1, amongst others. They are critical for sight, holding the crystalline lens in place and being necessary for accommodation. Zonulopathies refer to conditions in which there is a lack or disruption of zonular support to the lens and may clinically be manifested as ectopia lens (EL)-defined as subluxation of the lens outside of the pupillary plane or frank displacement (dislocation) into the vitreous or anterior segment.
View Article and Find Full Text PDFNd:YAG Laser Application for the Treatment of Retained Lens Fragment in the Anterior Chamber Following Cataract Surgery.
Turk J Ophthalmol
December 2024
University of Health Sciences Türkiye, Ulucanlar Eye Training and Research Hospital, Clinic of Ophthalmology, Ankara, Türkiye.
Cataract surgery is the most frequently performed surgery worldwide. Although it is an effective surgical treatment option for improving patients' visual acuity, various complications can occur postoperatively. One such complication is the presence of retained lens material in the anterior chamber, which can lead to intraocular inflammation, increased intraocular pressure, corneal edema, and endothelial cell loss.
View Article and Find Full Text PDFClinical spectrum of bilateral microspherophakia and risk factors associated with poor visual outcomes following lensectomy surgery - A multicentric study.
Indian J Ophthalmol
December 2024
The Bodhya Eye Consortium, India.
Purpose: To study the clinical profile of patients with microspherophakia and the factors associated with poor vision following lensectomy surgery.
Methods: A multicenter, retrospective, cross-sectional analysis was conducted from January 2010 to June 2022 on patients diagnosed with microspherophakia.
Results: A total of 102 eyes from 51 patients were enrolled, of whom 24 (47.
Transcapsular scleral fixation of the standard capsular tension ring and in-the-bag intraocular lens implantation for severely subluxated lenses.
Int J Ophthalmol
December 2024
School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Aim: To present a technique of transcapsular scleral fixation of the standard capsular tension ring (CTR) through equatorial capsulotomy and in-the-bag intraocular lens (IOL) implantation in subluxated lenses.
Methods: This retrospective consecutive case series included patients with subluxated lenses by more than 180 degrees who underwent lens extraction, transcapsular scleral fixation of the standard CTR through equatorial capsulotomy, in-the-bag IOL implantation and with at least 6mo follow-up. Preoperative and postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), complications, and postoperative IOL tilt and decentration were recorded.
Simple ab externo lens capsule removal in intraocular lens reuse and intrascleral fixation for intracapsular lens dislocation: A case report.
Medicine (Baltimore)
December 2024
Department of Ophthalmology, Saitama Red Cross Hospital, Saitama, Japan.
Background: This study aimed to report and recall a simple method to remove the lens capsule ab externo when performing intrascleral fixation of an intracapsular intraocular lens (IOL) dislocation with reuse of the IOL.
Case Presentation: A 43-year-old Japanese male patient underwent pars plana vitrectomy, phacoemulsification, and IOL fixation for rhegmatogenous retinal detachment in the right eye 10 years prior. A 3-piece IOL was intraocularly fixed during the initial procedure.
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