Objective: To explore the effects of essential amino acid (EAA) supplementation on high-intensity interval training (HIIT) fatigue, perceived exertion, and training progression in overweight and obese adults. A secondary aim was to explore potential sex-differences on these outcomes.
Methods: Thirty-seven untrained adults (51% female; 36.2 ± 5.9 yrs; 35.5 ± 6.7% body fat) completed eight weeks of HIIT, 2d/wk on a cycle ergometer, either with EAA supplementation (HIIT + EAA; 3.6 g of EAA twice daily, 30 minutes pre and post HIIT) or without supplementation (HIIT). Heart rate (HR) and ratings of perceived exertion (RPE) were recorded throughout each session as indices of within training fatigue. Time to exhaustion (TTE) was recorded for the final interval of each session. Workload progression was determined by change in watts. Differences between groups (with and without EAA) were evaluated at 1wk, 4wks, and 8wks by repeated measure ANOVAs (α = 0.05).
Results: There were no differences in TTE ( = 0.983) or workload progression ( = 0.655) with EAA supplementation at any time point. HR and RPE within HIIT sessions were not significantly different with EAA supplementation at any time point ( > 0.05). Results were similar when evaluating males and females separately, but in females, RPE was significantly lower with EAA supplementation at 4wks (Δ: 1.1-2.2; = 0.016).
Conclusion: EAA supplementation did not extend TTE during exercise or enhance workload progression across eight weeks of HIIT in untrained, overweight and obese adults. However, EAA consumed 30 minutes before exercise may reduce perceived exertion during the first four weeks of training in women, which may have implications for overall exercise enjoyment and long-term adherence.
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http://dx.doi.org/10.1080/07315724.2022.2060373 | DOI Listing |
J Transl Med
January 2025
Dipartimento di Psicologia e Scienze della Salute, Università Telematica Pegaso, Centro Direzionale, Via Porzio, Isola F2, Naples, 80143, Italy.
Background: Although little is yet known about the long-term maintenance of very low-energy ketogenic therapy (VLEKT) effects on body composition, muscle strength and inflammation, it is plausible to assume that changes may occur, particularly during the steps following the ketogenic step, due to the loss of the protective effects of ketones and the concomitant reintroduction of carbohydrates. For this reason, the present study aimed to evaluate the effects of supplementation with 8 g per day of essential amino acids (EAAs) on these parameters.
Methods: A total of 68 women of reproductive age and with grade I obesity who had completed 45 days of the ketogenic phase with VLEKT (KeNuT protocol) and 40 days of non-ketogenic phase of KeNuT protocol with VLEKT (phase 3, fruit reintroduction) were included in the study.
Essential amino acid (EAA) supplementation, including conditionally essential amino acid (CEAA) and branched-chain amino acids (BCAA) supplementation, has been suggested as a mechanism to optimize patient outcomes by counteracting the atrophy associated with orthopedic procedures. We sought to investigate the effect of EAA supplementation in the perioperative period on patients undergoing orthopedic and spine surgery, specifically whether it is associated with (1) reductions in postoperative muscle atrophy and (2) improved postoperative function including range of motion, strength, and mobility. We conducted a systematic review of the literature.
View Article and Find Full Text PDFNutrients
November 2024
IBD Unit, National Institute of Gastroenterology-IRCCS, 70013 Castellana Grotte, Italy.
Background: More than half of patients with Crohn's disease develop intestinal fibrosis induced intestinal obstruction with debilitating symptoms throughout their disease course. The incidence of stricture formation in CD has remained unchanged over the last several decades. Factors promoting intestinal fibrosis are currently unclear, but diet may represent an underestimated risk factor for intestinal fibrosis by modification of both the host immune response and intestinal microbial composition.
View Article and Find Full Text PDFVet World
September 2024
Research Center for Horticulture, Research Organization for Agriculture and Food, National Research and Innovation Agency, Indonesia.
Schizophrenia (Heidelb)
November 2024
Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
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