Eight new phenethoxy derivatives, trichoasperellins A-H (-), were isolated from the endophytic fungus G10 isolated from the medicinal plant L. The structures of these compounds were elucidated from spectroscopic data, -based configurational analysis, and Mosher's methods. Compounds - and - bear one or two multioxidized C moieties with the same carbon skeleton. The carbon skeletons of compounds - are new, all containing three moieties connected via two acetal carbons similar to those of disaccharide glycosides. Compound inhibited nitric oxide production with an IC value of 48.3 μM, comparable to that of the positive control indomethacin (IC, 42.3 μM).
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