X-ray micro-tomography systems often suffer from high levels of noise. In particular, severe ring artifacts are common in reconstructed images, caused by defects in the detector, calibration errors, and fluctuations producing streak noise in the raw sinogram data. Furthermore, the projections commonly contain high levels of Poissonian noise arising from the photon-counting detector. This work presents a 3-D multiscale framework for streak attenuation through a purposely designed collaborative filtering of correlated noise in volumetric data. A distinct multiscale denoising step for attenuation of the Poissonian noise is further proposed. By utilizing the volumetric structure of the projection data, the proposed fully automatic procedure offers improved feature preservation compared with 2-D denoising and avoids artifacts which arise from individual filtering of sinograms.
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http://dx.doi.org/10.1107/S1600577522002739 | DOI Listing |
Thromb Haemost
January 2025
Yale University Center for Outcomes Research and Evaluation, Boston, United States.
No abstract for this Commentary/Viewpoint. Glad to add if the Editorial Office sees necessary.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
January 2025
Librarian, Vidyavardhaka Law College, Mysore, Karnataka, 570 001, India.
Purpose: Research on vestibular function tests has advanced significantly over the past century. This study aims to evaluate research productivity, identify top contributors, and assess global collaboration to provide a comprehensive overview of trends and advancements in the field.
Method: A scientometric analysis was conducted using publications from the Scopus database, retrieved on January 5, 2024.
Commun Biol
January 2025
Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Single cell studies have transformed our understanding of cellular heterogeneity in disease but the need for fresh starting material can be an obstacle, especially in the context of international multicenter studies and archived tissue. We developed a protocol to obtain high-quality cells and nuclei from dissected human skeletal muscle archived in the preservative Allprotect® Tissue Reagent. After fluorescent imaging microscopy confirmed intact nuclei, we performed four protocol variations that compared sequencing metrics between cells and nuclei enriched by either filtering or flow cytometry sorting.
View Article and Find Full Text PDFAm J Pharm Educ
November 2024
University of Maryland School of Pharmacy, Baltimore, MD, USA.
Objective: This study examined the alignment between and changes within the tasks performed by pharmacists and skills sought by pharmacist employers from 2012 to 2022.
Methods: The United States Department of Labor's Occupational Information Network (O*NET) surveys a random sample of employees in targeted occupations every 5 years and provides a publicly available database allowing exploration of the frequency with which essential tasks are performed and perceived relevance and importance. Lightcast (formerly Burning Glass) provides labor market analytics of job advertisements; cross-sectional and longitudinal data can be filtered according to occupation, industry, location, and area of specialty.
Front Neurol
December 2024
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Background/objective: Preventive medications are crucial in migraine prevention. In cases of refractory migraine headaches, multiple medications may be required. We seek to identify a comprehensive list of preventive migraine headache medications that can be used as two, three, and four drug combinations without drug-drug interactions.
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