A man in his twenties was admitted to the Department of Surgery for abdominal pain with intermittent worsening over 12 hours. Investigation revealed a disorder rarely seen in Norwegian hospitals.
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Effects of Food on the Pharmacokinetics and Safety of HA121-28 Tablet, a Novel Multi-Targeting Tyrosine Kinase Inhibitor, in Healthy Chinese Subjects: A Phase I Clinical Trial.
Drug Des Devel Ther
January 2025
Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Purpose: HA121-28, a novel multi-targeting tyrosine kinase inhibitor, has dual efficacy against tumor growth and neovascularization. The objectives of this study were to assess the effect of high-fat and high-calorie food on the pharmacokinetic (PK) profile and safety of HA121-28 tablet in healthy subjects.
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Illnesses and Diseases Constitute a Quarter of Medical Conditions in an Under-21 National Football Team.
J Sport Rehabil
January 2025
Department of Hand Surgery, Bridge Hospital, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.
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Highly specific amyloid and tau PET ligands for ATN classification in suspected Alzheimer's disease patients.
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Department of Radiological Sciences, School of Health Science, Fukushima Medical University, 10-6 Sakae, Fukushima City, Fukushima, 960-8516, Japan.
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J Int Assoc Provid AIDS Care
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View Article and Find Full Text PDFStrength and size relationships of toe flexor muscles in three different functional force production tasks.
Acta Bioeng Biomech
September 2024
Institute of Advanced Research for Sport and Health Science, Ritsumeikan University, Japan.
: Toe flexor strength (TFS) has been determined to evaluate the toe flexor muscle function. However, it is unclear how strength and size relationships of toe flexor muscles vary depending on the toes intended for force production. We aimed to clarify this by examining the relationship between TFS and toe flexor muscle size, and hypothesized TFS produced by all toes (TFS-All), the great toe (TFS-Great) and lesser toes (TFS-Lesser) would be specifically associated with the size of the muscles specialized in each corresponding toe flexion.
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