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Challenges in Diagnosing Rickettsial Infection: A Case Report of Rickettsia conorii in a Pediatric Patient in Iran.
Pediatr Infect Dis J
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National Reference Laboratory for Plague, Tularemia and Q Fever.
Mediterranean spotted fever has recently been reported in Iran, yet it continues to be overlooked by healthcare professionals in the country. This case report details a 19-month-old child who presented with fever, edema and skin rashes and was initially misdiagnosed. Subsequent testing revealed a Mediterranean spotted fever infection through IgG seroconversion.
View Article and Find Full Text PDFCases of high-consequence infectious diseases identified in the UK, 1962-2023.
J Med Microbiol
March 2025
NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, UK.
The management of patients with acute infectious diseases can present significant challenges, especially if the causative agent has a propensity for person-to-person transmission. In such cases, effective patient management is dependent on both rapid identification of disease and the provision of necessary medical care while adhering to suitable infection prevention and control measures to reduce the potential for onwards transmission. The UK has operated a defined system for managing patients with high-consequence infectious diseases (HCIDs) since the 1970s, when protocols were first implemented following the first descriptions of several viral haemorrhagic fever diseases, including Marburg virus disease, Lassa fever and Ebola virus disease (EVD).
View Article and Find Full Text PDFTemporal and Spatial Effects of Extreme Drought Events on Human Epidemics over Ancient China in 1784-1787 CE.
Environ Health
March 2025
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Extreme drought events can impact human health, notably triggering epidemics that impose significant global health and economic burdens. Understanding these effects and developing response strategies is crucial. However, there is limited epidemiological evidence on how climate change influenced ancient epidemics before large-scale urbanization and frequent population movements.
View Article and Find Full Text PDFMalagasy flea microbiota results from a combination of vertically transmitted and environmentally acquired microbes.
Sci Rep
March 2025
Université de La Réunion, Unité Mixte de Recherche Processus Infectieux en Milieu Insulaire Tropical (UMR PIMIT), CNRS 9192, INSERM 1187, IRD 249, Plateforme Technologique CYROI, Sainte Clotilde, La Réunion, France.
Fleas (Insecta, Siphonaptera) are the known vectors of serious bacterial pathogens, such as Yersinia pestis and Rickettsia typhi. The microbiota of fleas has been poorly investigated although it has a known influence on vector competence. Here, we report and analyse the microbiota of 577 flea specimens from Madagascar, a hotspot of plague transmission.
View Article and Find Full Text PDFMolecular detection and characterization of , , and from peri-domestic fleas in Uganda.
Infect Ecol Epidemiol
March 2025
College of Veterinary Medicine, Makerere University, Kampala, Uganda.
Fleas transmit a variety of zoonotic agents whose epidemiology and public health risk remains poorly understood in sub-Saharan Africa, including Uganda particularly outside plague-endemic areas. Common flea-borne zoonotic agents include and . The study aimed at detecting and characterising flea-borne pathogens in peridomestic environments in Uganda.
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