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Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication. | LitMetric

AI Article Synopsis

  • Titanium dental implants represent a significant market in the U.S., valued at billions.
  • Bacterial biofilm growth on these implants can lead to serious issues like gingivitis and implant failure, resulting in costly treatments.
  • The study showcases the use of advanced microrobots, powered by magnetic fields and photoactive materials, to effectively eliminate biofilm on titanium implants, highlighting their potential for precision medicine.

Article Abstract

Titanium dental implants are a multibillion dollar market in the United States alone. The growth of a bacterial biofilm on a dental implant can cause gingivitis, implant loss, and expensive subsequent care. Herein, we demonstrate the efficient eradication of dental biofilm on titanium dental implants via swarming magnetic microrobots based on ferromagnetic (FeO) and photoactive (BiVO) materials through polyethylenimine micelles. The ferromagnetic component serves as a propulsion force using a transversal rotating magnetic field while BiVO is the photoactive generator of reactive oxygen species to eradicate the biofilm colonies. Such photoactive magnetically powered, precisely navigated microrobots are able to destroy biofilm colonies on titanium implants, demonstrating their use in precision medicine.

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Source
http://dx.doi.org/10.1021/acsnano.2c02516DOI Listing

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